DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rox8 and Cstf2t

DIOPT Version :9

Sequence 1:NP_001262897.1 Gene:Rox8 / 42848 FlyBaseID:FBgn0005649 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_112539.2 Gene:Cstf2t / 83410 MGIID:1932622 Length:632 Species:Mus musculus


Alignment Length:235 Identity:61/235 - (25%)
Similarity:103/235 - (43%) Gaps:47/235 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKII--REPGNDP-YAFIEYSNYQAATTAL 62
            ||.|. ::::|||:....:|:.|..:||.:|.|.|.:::  ||.|... |.|.||.:.:.|.:|:
Mouse    11 MDRSL-RSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAM 74

  Fly    63 TAMNKRLFLEKEIKVNWATSPGNQ-------PKTDISSHHHIFVGD-LSPEIETETLREAFAP-- 117
            ..:|.|.|..:.::|:.|.|..|:       |...|....:   || :.||...|::..|.|.  
Mouse    75 RNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPY---GDPIDPEDAPESITRAVASLP 136

  Fly   118 ----FGEISNCRI-VRDPHTMKSK--------GYAFVS---FVKKAEAENAIQAMNGQWIGSRSI 166
                |..:...:: |::.|.....        .||.:.   .::..:.|.|::.::      |.|
Mouse   137 PEQMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILH------RKI 195

  Fly   167 RTNWSTRKLPPPREPSKGGGQGG----GMGG-GPGNGSGV 201
            ..   |..:|...:|..|.|.||    |.|| |||...|:
Mouse   196 HV---TPLIPGKSQPVSGPGPGGPGPSGPGGPGPGPAPGL 232

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rox8NP_001262897.1 ELAV_HUD_SF 5..274 CDD:273741 58/231 (25%)
RRM1_TIA1_like 9..80 CDD:240798 23/73 (32%)
RRM2_TIA1_like 96..170 CDD:240799 16/92 (17%)
RRM3_TIA1_like 221..294 CDD:240800
Cstf2tNP_112539.2 RRM <16..>109 CDD:223796 27/92 (29%)
RRM_CSTF2_CSTF2T 18..92 CDD:241115 23/73 (32%)
CSTF2_hinge 113..191 CDD:291025 14/80 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 201..296 13/32 (41%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 365..433
8 X 5 AA tandem repeats of M-E-T-R-[AG] 428..466
12 X 5 AA tandem repeats of G-[AT]-G-[MI]-Q 508..565
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 519..590
CSTF_C 588..628 CDD:291002
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0724
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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