DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rox8 and Srsf4

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001356237.1	Gene:	Srsf4 / 57317	MGIID:	1890577	Length:	496	Species:	Mus musculus

Alignment Length:	200	Identity:	47/200 - (23%)
Similarity:	78/200 - (39%)	Gaps:	39/200 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 GDLSPEIETETLREAFAPFGEISNCRIVRDP-HTMKSKGYAFVSFVKKAEAENAIQAMNGQWI-G 162
            |:.||..|::|  .......|.|:..|.|.. .|:..:.|.||.|....:|::|:..:||:.: |
Mouse     5 GNGSPHWESKT--HILLVLAEDSHVHIQRKACGTVVGQRYGFVEFDDLRDADDAVYELNGKDLCG 67

  Fly   163 SRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCGG 227
            .|.|        :...|.|.:.|..|.|.     :|.|.:.|.|..:       .|...|.|
Mouse    68 ERVI--------VEHARGPRRDGSYGSGR-----SGYGYRRSGRDKY-------GPPTRTEY--- 109

  Fly   228 FPPNVISDDL--------MHKHFVQFGPIQDVRVFKD-KGFSFIKFVTKEAAAHAIEHTHNSEVH 283
               .:|.::|        :..:..|.|.:......|. |....|:||:......|:|....:||:
Mouse   110 ---RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVN 171

  Fly   284 GNLVK 288
            |..::
Mouse   172 GRKIR 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	42/184 (23%)
		RRM1_TIA1_like	9..80	CDD:240798
		RRM2_TIA1_like	96..170	CDD:240799	21/71 (30%)
		RRM3_TIA1_like	221..294	CDD:240800	16/76 (21%)
Srsf4	NP_001356237.1	RRM_SF	<42..77	CDD:388407	11/42 (26%)
		RRM2_SRSF4_like	109..180	CDD:241044	15/73 (21%)
		U2AF_lg	250..>361	CDD:273727
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810