Protein Alignment Rox8 and rbm4.1

DIOPT Version :10

• Sequence 1: NP_732944.2
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_955999.1
• Gene: rbm4.1 / 573001
• ZFINID: ZDB-GENE-030131-3902
• Length: 419
• Species: Danio rerio
• Alignment Length: 476
• Identity: 96/476 - (20%)
• Similarity: 166/476 - (34%)
• Gaps: 124/476 - (26%)

  Fly     9 LYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDPYAFIEYSNYQAATTALTAMNKRLFLEK 73
            ::||||..:.:.:.:.:|||..|.:..|.|::.     :.|:...:...|..|:  .|...::..
Zfish     4 IFVGNLSPNTTAEEIRSLFSQYGKISECDIVKN-----FGFVHMDSKSEADEAI--QNLHHYMLN 61

  Fly    74 EIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGY 138
            .:.:|...|.| :|||....|    ||::|.....:.||..|..:|.:..|.||:|        |
Zfish    62 GMAMNVEMSKG-KPKTSTKPH----VGNISSSCTNQELRAKFEEYGPVVECDIVKD--------Y 113

  Fly   139 AFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKG 203
            |||...:..:|..||..::......:.:....||.:|..                .||.|... |
Zfish   114 AFVHMERVEDAMEAISGLDNTAFQGKLMSVKLSTSRLRT----------------APGMGERT-G 161

  Fly   204 SQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFK---DKGFSFIKFV 265
            ..|...|..:::..|.:..   |.:.....|:.        |||::    |.   |:|..|.:..
Zfish   162 CYRCGQEGHWSKECPLDQN---GSYREGPSSEG--------FGPVR----FDSGGDRGRGFHRGF 211

  Fly   266 TKE-------AAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAA 323
            :.|       |.:|.........|.|      :|:..|.:::......|.....|..::|.|..:
Zfish   212 SGEPAYAGSFAPSHGFTRGAGYAVPG------YGRGAGFESAMGYGMPAGYGVGADNSMAPVYGS 270

  Fly   324 NAAV-AAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYA----YQQM------GYWY- 376
            .||. .:|...||              |:|...:.......:.||.    |::.      |.::
Zfish   271 EAAYGTSGMAYPG--------------ALPAYPIRRPPYEERDPYGVVDFYEKYRARPYGGSYFE 321

  Fly   377 -----------PPATYPT------TQMQTQYMQQGYYPYAYPTSA---QQAGGVPCIQFSAAGY- 420
                       ||.:.|.      :.:...|.:....|...|||:   ::...|......|.||
Zfish   322 DRRAVQPPVPPPPTSTPVVRERLPSNLVDPYERHPLPPPPAPTSSYYVRERSPVRRAPHEAEGYA 386

  Fly   421 ---------RMVPPNVAWGVP 432
                     .::|...|:.||
Zfish   387 YERSRLSPISVLPRTAAYDVP 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_732944.2	RRM1_TIA1_like	9..80	CDD:409788	15/70 (21%)
		RRM2_TIA1_like	96..170	CDD:409789	18/73 (25%)
		RRM_SF	221..292	CDD:473069	14/80 (18%)
rbm4.1	NP_955999.1	RRM1_RBM4	2..68	CDD:410018	15/70 (21%)
		RRM2_RBM4	78..144	CDD:410019	19/77 (25%)
		PTZ00368	148..>182	CDD:173561	8/53 (15%)
		ZnF_C2HC	161..176	CDD:197667	3/14 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	322..341		3/18 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	349..371		5/21 (24%)