DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rox8 and hnrnpm

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_005170511.1	Gene:	hnrnpm / 555643	ZFINID:	ZDB-GENE-030131-6898	Length:	715	Species:	Danio rerio

Alignment Length:	130	Identity:	33/130 - (25%)
Similarity:	60/130 - (46%)	Gaps:	16/130 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 QPKTDISSHHHIFVGDLSPEIETETLREAF-APFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEA 149
            :|.::.:..:.:||.::..:::.:||::.. ...||::....:.|... ||:|.|.|.|..:...
Zfish    39 EPYSNPNKRYSVFVSNIPYDVKWQTLKDLMKEKVGEVTYVEHLMDGEG-KSRGCAVVEFRTEELM 102

  Fly   150 ENAIQAMNGQWIGSRSIRTNWSTRKLPPPRE--------------PSKGGGQGGGMGGGPGNGSG 200
            :.|::.:|...:..|.::.......:...||              |..|||.|||||||.|.|.|
Zfish   103 KKAVEKVNKHVMNGRPLKVKEDPDGVISQREANRGHGGGGGGGGPPGMGGGMGGGMGGGMGGGMG 167

Fly 201 200
Zfish 168 167

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	33/130 (25%)
		RRM1_TIA1_like	9..80	CDD:240798
		RRM2_TIA1_like	96..170	CDD:240799	16/74 (22%)
		RRM3_TIA1_like	221..294	CDD:240800
hnrnpm	XP_005170511.1	RRM	<19..>122	CDD:223796	17/83 (20%)
		HnRNP_M	20..47	CDD:288396	1/7 (14%)
		RRM1_hnRNPM	49..124	CDD:241101	16/75 (21%)
		RRM	<215..>309	CDD:223796
		RRM2_hnRNPM	233..308	CDD:241103
		RRM3_hnRNPM	639..715	CDD:241105
		RRM	<640..>715	CDD:223796
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810