DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rox8 and SF2

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001247139.1	Gene:	SF2 / 53443	FlyBaseID:	FBgn0283477	Length:	255	Species:	Drosophila melanogaster

Alignment Length:	213	Identity:	54/213 - (25%)
Similarity:	87/213 - (40%)	Gaps:	38/213 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWI 161
            |:||:|.|:|.|:.:::.|..||:::    ..|....:...:|||.|....:|::|::|.:|...
  Fly     9 IYVGNLPPDIRTKDIQDLFHKFGKVT----FVDLKNRRGPPFAFVEFEDARDADDAVKARDGYDY 69

  Fly   162 GSRSIRTNWSTRKLPPPREPSKGGGQGGGM------GGG--PGNGSGVKGSQRHTFEEVYNQSSP 218
            ....:|..:       ||....|..:||..      |||  .|.|...|.||..
  Fly    70 DGYRLRVEF-------PRGGGPGSYRGGNRNDRSRDGGGRMGGRGPPAKRSQYR----------- 116

  Fly   219 TNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEV- 282
                |...|.|.:....|| ..|..:.|.:.....:|| |...::|:..|...:||:...:|..
  Fly   117 ----VMVTGLPASGSWQDL-KDHMREAGDVCFADTYKD-GSGVVEFLRHEDMKYAIKKLDDSRFR 175

  Fly   283 -HGNLVKCFWGKENGGDN 299
             |...|.....:|:.|||
  Fly   176 SHEGEVAYIRVREDSGDN 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	45/184 (24%)
		RRM1_TIA1_like	9..80	CDD:240798
		RRM2_TIA1_like	96..170	CDD:240799	20/72 (28%)
		RRM3_TIA1_like	221..294	CDD:240800	17/74 (23%)
SF2	NP_001247139.1	RRM_SF	3..80	CDD:418427	20/81 (25%)
SF2	NP_001247139.1	RRM2_SRSF1_like	115..188	CDD:410013	17/89 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900