DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rox8 and B52

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001014619.2	Gene:	B52 / 41670	FlyBaseID:	FBgn0004587	Length:	355	Species:	Drosophila melanogaster

Alignment Length:	231	Identity:	50/231 - (21%)
Similarity:	86/231 - (37%)	Gaps:	55/231 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDPYAFIEYSNYQAATTALTAMNKRLFLEK 73
            :|||.|...|.|..|...|...|..:...|     .:.|.|:|:.:|:.|..|:..:|.:..|.:
  Fly     6 VYVGGLPYGVRERDLERFFKGYGRTRDILI-----KNGYGFVEFEDYRDADDAVYELNGKELLGE 65

  Fly    74 EIKVNWA--TSPG-NQPKTD------------------------------ISSHHHIFVGDLSPE 105
            .:.|..|  |:.| |:.:.|                              :.:.:.:.|.:||..
  Fly    66 RVVVEPARGTARGSNRDRYDDRYGGRRGGGGGRYNEKNKNSRSSSRYGPPLRTEYRLIVENLSSR 130

  Fly   106 IETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNW 170
            :..:.|::.....||::    ..|.|..: :....|.|...::.:.||:.::...:..|.|..
  Fly   131 VSWQDLKDYMRQAGEVT----YADAHKQR-RNEGVVEFASLSDMKTAIEKLDDTELNGRRIHL-- 188

  Fly   171 STRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQR 206
                    .|..:||..||  |||.|.|.....|.|
  Fly   189 --------VEDRRGGRSGG--GGGSGRGRSRSSSSR 214

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	50/231 (22%)
		RRM1_TIA1_like	9..80	CDD:240798	19/70 (27%)
		RRM2_TIA1_like	96..170	CDD:240799	14/73 (19%)
		RRM3_TIA1_like	221..294	CDD:240800
B52	NP_001014619.2	RRM1_SRSF4_like	5..74	CDD:240783	20/72 (28%)
B52	NP_001014619.2	RRM2_SRSF4_like	120..191	CDD:241044	14/85 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810