Protein Alignment Rox8 and tia1

DIOPT Version :10

• Sequence 1: NP_732944.2
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: XP_012814227.2
• Gene: tia1 / 394890
• XenbaseID: XB-GENE-1002876
• Length: 389
• Species: Xenopus tropicalis
• Alignment Length: 486
• Identity: 190/486 - (39%)
• Similarity: 252/486 - (51%)
• Gaps: 113/486 - (23%)

  Fly     1 MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIRE-PGNDPYAFIEYSNYQAATTALTA 64
            |:|..|:|||||||...|:|.|::.:||.:||.||||:|.: .|||||.|:|:..::.|..:|.|
 Frog     1 MEEDLPRTLYVGNLSRDVTEPLILQVFSQLGPCKSCKMIMDTAGNDPYCFVEFFEHRHAAASLAA 65

  Fly    65 MNKRLFLEKEIKVNWATSPGNQPKTDISS----------HHHIFVGDLSPEIETETLREAFAPFG 119
            ||.|..:.||:||||||:|.:|.|...||          |.|:|||||||||.|:.::.||||||
 Frog    66 MNGRKIMGKEVKVNWATTPSSQKKDANSSSVVSTLRSQDHFHVFVGDLSPEITTDDIKAAFAPFG 130

  Fly   120 EISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKG 184
            .||:.|:|:|..|.|||||.||||..|.:|||||..|.|||:|.|.|||||:|||.|.|:...:
 Frog   131 RISDARVVKDMTTGKSKGYGFVSFFNKWDAENAIAQMGGQWLGGRQIRTNWATRKPPAPKSTYE- 194

  Fly   185 GGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQ 249
                             ..:::.|:|||.|||||:|.||||||.... :::.||.:.|..||.|.
 Frog   195 -----------------SNTKQLTYEEVVNQSSPSNCTVYCGGVTSG-LTEQLMRQTFSPFGQIM 241

  Fly   250 DVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAAS 314
            :||||.|||:||::|.:.|:|||||...:.:.:.|::|||:||||.
 Frog   242 EVRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKET------------------- 287

  Fly   315 ANVAAVAAANAAVAAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYAYQQMGYWYPPA 379
                               |..:...||::.|:            ||:  :|..|.|.|.||..|
 Frog   288 -------------------PDMLNPVQQVSEAS------------QIS--FPPPYGQWGQWYGGA 319

  Fly   380 TYPTTQMQTQYMQQGYYPYAYPTSAQQAGGVPCIQFSAAGYRMVPPNVA-WGVPGTVV---PGVT 440
                 |...||:..|:...||        ||....:|..||...|.:.| |..|...|   ||
 Frog   320 -----QQIGQYVPNGWQMPAY--------GVYGQAWSQQGYSQTPSSAATWVGPNYGVQPQPG-- 369

  Fly   441 AAAASAAAAANGSL-APQMMYSAAMPQYQTQ 470
                     .||:| ..|..|  .|..||||
 Frog   370 ---------QNGTLITNQTGY--RMAGYQTQ 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_732944.2	RRM1_TIA1_like	9..80	CDD:409788	36/71 (51%)
		RRM2_TIA1_like	96..170	CDD:409789	47/73 (64%)
		RRM_SF	221..292	CDD:473069	32/70 (46%)
tia1	XP_012814227.2	RRM1_TIA1	8..81	CDD:410027	37/72 (51%)
		RRM2_TIA1	104..181	CDD:410030	48/76 (63%)
		RRM3_TIAR	214..286	CDD:241064	34/72 (47%)