DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rox8 and Cstf2t

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	NP_001101056.1	Gene:	Cstf2t / 309338	RGDID:	1310026	Length:	629	Species:	Rattus norvegicus

Alignment Length:	235	Identity:	59/235 - (25%)
Similarity:	101/235 - (42%)	Gaps:	54/235 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKII--REPGNDP-YAFIEYSNYQAATTAL 62
            ||.|. ::::|||:....:|:.|..:||.:|.|.|.:::  ||.|... |.|.||.:.:.|.:|:
  Rat    11 MDRSL-RSVFVGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAM 74

  Fly    63 TAMNKRLFLEKEIKVNWATSPGNQ-------PKTDISSHHHIFVGD-LSPEIETETLREA----- 114
            ..:|.|.|..:.::|:.|.|..|:       |...|....:   || :.||...|::..|
  Rat    75 RNLNGREFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPY---GDPIDPEDAPESITRAVASLP 136

  Fly   115 ----FAPFGEISNC----------RIVRDPHTMKSKGYAFVS---FVKKAEAENAIQAMNGQWIG 162
                |....::..|          .::::|..    .||.:.   .::..:.|.|::.::
  Rat   137 PEQMFELMKQMKLCVQNSHQEARNMLLQNPQL----AYALLQAQVVMRIMDPEIALKILH----- 192

  Fly   163 SRSIRTNWSTRKLPPPREPSKGGGQGG----GMGGGPGNG 198
             |.|..   |..:|...:|..|.|.||    |..||||.|
  Rat   193 -RKIHV---TPLIPGKSQPVSGPGPGGPGGPGGPGGPGPG 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	56/231 (24%)
		RRM1_TIA1_like	9..80	CDD:240798	23/73 (32%)
		RRM2_TIA1_like	96..170	CDD:240799	15/96 (16%)
		RRM3_TIA1_like	221..294	CDD:240800
Cstf2t	NP_001101056.1	RRM	<16..>109	CDD:223796	27/92 (29%)
		RRM_CSTF2_CSTF2T	18..92	CDD:241115	23/73 (32%)
		CSTF2_hinge	113..191	CDD:291025	13/84 (15%)
		CSTF_C	585..625	CDD:291002
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900