DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rox8 and Srsf5

DIOPT Version :9

Sequence 1:	NP_001262897.1	Gene:	Rox8 / 42848	FlyBaseID:	FBgn0005649	Length:	470	Species:	Drosophila melanogaster
Sequence 2:	XP_038967784.1	Gene:	Srsf5 / 29667	RGDID:	3664	Length:	270	Species:	Rattus norvegicus

Alignment Length:	222	Identity:	36/222 - (16%)
Similarity:	84/222 - (37%)	Gaps:	65/222 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDPYAFIEYSNYQAATTALTAMNKRLFLEK 73
            :::|.|:.:..|..:...|...|.::...:.|     .:.|:|:.:.:.|..|:..::.:....:
  Rat     6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLKR-----GFGFVEFEDPRDADDAVYELDGKELCSE 65

  Fly    74 EIKVNWATS---------------PGNQPKTD------ISSHHHIFVGDLSPEIETETLREAFAP 117
            .:.:..|.:               ...:|:.|      :.:.:.:.|.:||..:..:.|::....
  Rat    66 RVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQ 130

  Fly   118 FGEISNCRIVRDPHTMK-SKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREP 181
            .||::    ..|.|..| ::|  .|.|....:.:|||:.::|:.|..|.|:.
  Rat   131 AGEVT----FADAHRPKLNEG--VVEFASYGDLKNAIEKLSGKEINGRKIKL------------- 176

  Fly   182 SKGGGQGGGMGGGPGNGSGVKGSQRHT 208
                               ::||:||:
  Rat   177 -------------------IEGSKRHS 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_001262897.1	ELAV_HUD_SF	5..274	CDD:273741	36/222 (16%)
		RRM1_TIA1_like	9..80	CDD:240798	10/70 (14%)
		RRM2_TIA1_like	96..170	CDD:240799	19/74 (26%)
		RRM3_TIA1_like	221..294	CDD:240800
Srsf5	XP_038967784.1	RRM1_SRSF5	5..74	CDD:410008	11/72 (15%)
Srsf5	XP_038967784.1	RRM2_SRSF5	99..179	CDD:410158	19/117 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0724
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810