Protein Alignment Rox8 and RBMX

DIOPT Version :10

• Sequence 1: NP_732944.2
• Gene: Rox8 / 42848
• FlyBaseID: FBgn0005649
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_002130.2
• Gene: RBMX / 27316
• HGNCID: 9910
• Length: 391
• Species: Homo sapiens
• Alignment Length: 167
• Identity: 47/167 - (28%)
• Similarity: 76/167 - (45%)
• Gaps: 18/167 - (10%)

  Fly    97 IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWI 161
            :|:|.|:.|...:.|...|..:|.|....:::|..|.||:|:|||:|...|:|::|.:.|||:.:
Human    10 LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSL 74

  Fly   162 GSRSIRTNWST-------RKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRH-------TFEEV 212
            ..::|:...:|       |:.|||  |.:..|...|:.||.|...|.:|....       .:...
Human    75 DGKAIKVEQATKPSFESGRRGPPP--PPRSRGPPRGLRGGRGGSGGTRGPPSRGGHMDDGGYSMN 137

  Fly   213 YNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQ 249
            :|.||.........|.||.  |.....|.....||::
Human   138 FNMSSSRGPLPVKRGPPPR--SGGPPPKRSAPSGPVR 172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rox8	NP_732944.2	RRM1_TIA1_like	9..80	CDD:409788
		RRM2_TIA1_like	96..170	CDD:409789	24/72 (33%)
		RRM_SF	221..292	CDD:473069	7/29 (24%)
RBMX	NP_002130.2	RRM_RBMX_like	7..86	CDD:409816	24/75 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..391		29/116 (25%)
		dnaA	165..>306	CDD:455861	2/8 (25%)
		RBM1CTR	173..217	CDD:400429	47/167 (28%)
		Necessary for the association to nascent RNAPII transcripts and nuclear localization	186..236
		Necessary for RNA-binding	333..391