DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Rox8 and Srsf1

DIOPT Version :9

Sequence 1:NP_001262897.1 Gene:Rox8 / 42848 FlyBaseID:FBgn0005649 Length:470 Species:Drosophila melanogaster
Sequence 2:NP_775550.2 Gene:Srsf1 / 110809 MGIID:98283 Length:248 Species:Mus musculus


Alignment Length:188 Identity:53/188 - (28%)
Similarity:82/188 - (43%) Gaps:29/188 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKG---YAFVSFVKKAEAENAIQAMNG 158
            |:||:|.|:|.|:.:.:.|..:|.|      ||......:|   :|||.|....:||:|:...:|
Mouse    18 IYVGNLPPDIRTKDIEDVFYKYGAI------RDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRDG 76

  Fly   159 QWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTV 223
            .......:|..:       ||. .:|.|:|||.|||.|...|..|.          .|..:...|
Mouse    77 YDYDGYRLRVEF-------PRS-GRGTGRGGGGGGGGGAPRGRYGP----------PSRRSENRV 123

  Fly   224 YCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSE 281
            ...|.||:....|| ..|..:.|.:....|::| |...::||.||...:|:....|::
Mouse   124 VVSGLPPSGSWQDL-KDHMREAGDVCYADVYRD-GTGVVEFVRKEDMTYAVRKLDNTK 179

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rox8NP_001262897.1 ELAV_HUD_SF 5..274 CDD:273741 51/179 (28%)
RRM1_TIA1_like 9..80 CDD:240798
RRM2_TIA1_like 96..170 CDD:240799 22/75 (29%)
RRM3_TIA1_like 221..294 CDD:240800 17/61 (28%)
Srsf1NP_775550.2 RRM1_SRSF1 12..90 CDD:410010 22/84 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 88..134 18/63 (29%)
RRM2_SRSF1 113..196 CDD:410160 19/79 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 191..248
Interaction with SAFB1. /evidence=ECO:0000250 198..247
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0724
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.