DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rox8 and srsf4

DIOPT Version :10

Sequence 1:NP_732944.2 Gene:Rox8 / 42848 FlyBaseID:FBgn0005649 Length:470 Species:Drosophila melanogaster
Sequence 2:XP_004911639.2 Gene:srsf4 / 100038227 XenbaseID:XB-GENE-493077 Length:741 Species:Xenopus tropicalis


Alignment Length:224 Identity:50/224 - (22%)
Similarity:86/224 - (38%) Gaps:38/224 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    97 IFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWI 161
            :::|.||.......:...|..||:|....:        ..||.||.|....:||:|:..|||:.:
 Frog     9 VYIGRLSHRARERDVERFFKGFGKIVEVDL--------KNGYGFVEFEDSRDAEDAVYEMNGREL 65

  Fly   162 -GSRSIRTNWSTRKLPPPREPSKG--GGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTV 223
             |.|.|        :...|.|.:.  .|.|...||....|..|:...|...|.:.::.|..:   
 Frog    66 CGERVI--------VEHARAPRRDIRSGYGYRKGGSDKYGPPVRTMYRLRVENLSSRCSWQD--- 119

  Fly   224 YCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHG---N 285
                     :.|.:.....|.:......|  :::|  .|:|.:......|:|....||::|   .
 Frog   120 ---------LKDFMRQAGEVTYADAHQRR--QNEG--VIEFRSYSDMRRALEKLDGSEINGRKIQ 171

  Fly   286 LVKCFWGKENGGDNSANNLNAAAAAAAAS 314
            ||:...|..|.|.:|.:...:.:..:.:|
 Frog   172 LVEDRAGSRNKGSSSRSRSRSRSRRSRSS 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rox8NP_732944.2 RRM1_TIA1_like 9..80 CDD:409788
RRM2_TIA1_like 96..170 CDD:409789 21/73 (29%)
RRM_SF 221..292 CDD:473069 13/73 (18%)
srsf4XP_004911639.2 RRM_SF 6..77 CDD:473069 21/83 (25%)
RRM_SF 104..176 CDD:473069 16/87 (18%)
PTZ00121 <248..716 CDD:173412
PRK12678 255..>469 CDD:237171
Blue background indicates that the domain is not in the aligned region.

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