Protein Alignment spas and DAA1

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_849842.1
• Gene: DAA1 / 842716
• AraportID: AT1G64110
• Length: 829
• Species: Arabidopsis thaliana
• Alignment Length: 806
• Identity: 230/806 - (28%)
• Similarity: 360/806 - (44%)
• Gaps: 199/806 - (24%)

  Fly     9 SSSSASSSSTKSPIKSS----SGAGSSGGGLGGRQSTHRSSSASNVAAVVAGGSSAAGGGSSSNR 69
            |.::.|||..:||.:|:    ||..||...|..|:                  .|.|||  :..|
plant   151 SGNTESSSFKRSPSESALEQLSGLFSSFSILPQRE------------------ESKAGG--TLRR 195

  Fly    70 RSPG-----SSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPI----IFL 125
            :|.|     ||.:|..:        |......|....:....:||.::     ||.|:    .:.
plant   196 QSSGVDIKSSSMEGSSN--------PPKLRRNSSAAANISNLASSSNQ-----VSAPLKRSSSWS 247

  Fly   126 FNVLRSLIYQLFCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLNHPSELNREGDGQE 190
            |:. :.|:..|:.:..|:..|:..|:|   .||      |:|.....|::.|...:|       .
plant   248 FDE-KLLVQSLYKVLAYVSKANPIVLY---LRD------VENFLFRSQRTYNLFQKL-------L 295

  Fly   191 QQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISK-ALKIDEENEGHK 254
            |:||.                            |:|....    |..:..|: |.:|||     |
plant   296 QKLSG----------------------------PVLILGS----RIVDLSSEDAQEIDE-----K 323

  Fly   255 ELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFL-ALREQDL--- 315
            ..|:..|...|:..||...:..|.      .:.:|..:.:||.    .:|.|.: .|.|.||
plant   324 LSAVFPYNIDIRPPEDETHLVSWK------SQLERDMNMIQTQ----DNRNHIMEVLSENDLICD 378

  Fly   316 QMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPM----------KLRVRSSGYGPKATTSAQPT 370
            .::.:|.     |:.:.......|.:::.::...|          ||.:.|.......:...:..
plant   379 DLESISF-----EDTKVLSNYIEEIVVSALSYHLMNNKDPEYRNGKLVISSISLSHGFSLFREGK 438

  Fly   371 ASGR-KLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPP 434
            |.|| ||...:|...:..|..:|........|.|:|.: :.:|.|.|          .:.:.||.
plant   439 AGGREKLKQKTKEESSKEVKAESIKPETKTESVTTVSS-KEEPEKEA----------KAEKVTPK 492

  Fly   435 QRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLIL--DEIVEGGAKVEWTDIAGQDVAKQALQE 497
            .....|.|.                 .|:::...::  :||     .|.:.||...|..|::|||
plant   493 APEVAPDNE-----------------FEKRIRPEVIPAEEI-----NVTFKDIGALDEIKESLQE 535

  Fly   498 MVILPSVRPELFT-GLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGE 561
            :|:||..||:||| ||..|.:|:|||||||.|||:||:|:|.|..|:|:|:|.:::|||:.|:.|
plant   536 LVMLPLRRPDLFTGGLLKPCRGILLFGPPGTGKTMLAKAIAKEAGASFINVSMSTITSKWFGEDE 600

  Fly   562 KLVRALFAVARHMQPSIIFIDEVDSLLSERSS-SEHEASRRLKTEFLVEFDGLPGNPDGDRIVVL 625
            |.|||||.:|..:.|:|||:|||||:|.:|:. .||||.|::|.||:..:|||...| |:||:||
plant   601 KNVRALFTLASKVSPTIIFVDEVDSMLGQRTRVGEHEAMRKIKNEFMSHWDGLMTKP-GERILVL 664

  Fly   626 AATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQ--GSPLDTEALRRLAKITDGYSG 688
            ||||||.:||||.:|||.:|:.|.||..:.||.:|..||.|:  ...||   .:.||.:|:||:|
plant   665 AATNRPFDLDEAIIRRFERRIMVGLPAVENREKILRTLLAKEKVDENLD---YKELAMMTEGYTG 726

  Fly   689 SDLTALAKDAALEPIRELNVEQVKCLD----------------------ISAMRAITEQDFHSSL 731
            |||..|...||..|:||| ::|.:..|                      :..:|.:..|||..:.
plant   727 SDLKNLCTTAAYRPVREL-IQQERIKDTEKKKQREPTKAGEEDEGKEERVITLRPLNRQDFKEAK 790

  Fly   732 KRIRRSVAPQ--SLNSYEKWSQDYGD 755
            .::..|.|.:  .:...::|::.||:
plant   791 NQVAASFAAEGAGMGELKQWNELYGE 816

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	18/78 (23%)
		RecA-like_spastin	484..648	CDD:410932	92/165 (56%)
		AAA_lid_3	676..727	CDD:465537	20/72 (28%)
		Vps4_C	<722..754	CDD:462762	6/33 (18%)
DAA1	NP_849842.1	McrB	<449..>581	CDD:441011	51/164 (31%)
		P-loop containing Nucleoside Triphosphate Hydrolases	522..687	CDD:476819	92/165 (56%)
		AAA_lid_3	711..755	CDD:465537	20/47 (43%)