Protein Alignment spas and AT1G50140

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_175433.2
• Gene: AT1G50140 / 841436
• AraportID: AT1G50140
• Length: 1003
• Species: Arabidopsis thaliana
• Alignment Length: 637
• Identity: 194/637 - (30%)
• Similarity: 302/637 - (47%)
• Gaps: 133/637 - (20%)

  Fly   221 PGDPLLAKQKHHHRRAFEYISKALKI------DEENEGHKELAIE------LYRKGIKELE---- 269
            ||.||.:.|:   ...:|.|...:.:      |:.:||.::...|      ::...:|:|:
plant   387 PGRPLSSGQR---GEVYEVIGNRVAVIFEYGDDKTSEGSEKKPAEQPQMLPIHWLDVKDLKYDLD 448

  Fly   270 ----DG-IAVDC--------------------WSGRG-------DVWDRAQRLHDKMQTNLSM-- 300
                || ||::.                    |..|.       :..|:.:.:.||:...:.|
plant   449 MQAVDGYIAMEALNEVLQSIQPLIVYFPDSTQWLSRAVPKTRRKEFVDKVKEMFDKLSGPIVMIC 513

  Fly   301 --------ARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKLRVRSS 357
                    :::|..|..:.....::.:|.|..|...|..:...|:.|..:..:....|:|
plant   514 GQNKIETGSKEREKFTMVLPNLSRVVKLPLPLKGLTEGFTGRGKSEENEIYKLFTNVMRL----- 573

  Fly   358 GYGPKATTS----AQPTASGRKLTIGSKRPVN--LAVANKSQTLPRNLGSKTSVGAV-QRQPAK- 414
             :.||...:    .:.....|::.| |:..:|  |....:.:.|..:|....:.|.: .:|.|:
plant   574 -HPPKEEDTLRLFKKQLGEDRRIVI-SRSNINELLKALEEHELLCTDLYQVNTDGVILTKQKAEK 636

  Fly   415 ---------TAATP-PAVRRQFSSGRNTPPQRS---------RTPINNNGPSGSGASTPVVSVKG 460
                     .|:.| |.|:    .||.:.|:.|         :...|:..||
plant   637 AIGWAKNHYLASCPVPLVK----GGRLSLPRESLEISIARLRKLEDNSLKPS------------- 684

  Fly   461 VEQKLVQLILDE---------IVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFT--GLRA 514
              |.|..:..||         :..|...|::.||...:..|:||.|:||||..|||||.  .|..
plant   685 --QNLKNIAKDEYERNFVSAVVAPGEIGVKFEDIGALEDVKKALNELVILPMRRPELFARGNLLR 747

  Fly   515 PAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSII 579
            |.||:|||||||.||||||:|:|||..|.|::|:.::||||:.||.|||.:|||:.|..:.|.||
plant   748 PCKGILLFGPPGTGKTLLAKALATEAGANFISITGSTLTSKWFGDAEKLTKALFSFATKLAPVII 812

  Fly   580 FIDEVDSLLSER-SSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFT 643
            |:||:||||..| .||||||:||::.||:..:||| .:.|..||::|.|||||.:||:|.:||..
plant   813 FVDEIDSLLGARGGSSEHEATRRMRNEFMAAWDGL-RSKDSQRILILGATNRPFDLDDAVIRRLP 876

  Fly   644 KRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNV 708
            :|:||.|||.:.|..:|...|..:....|.: ..:|||.|:|||||||..|...||..|::||..
plant   877 RRIYVDLPDAENRLKILKIFLTPENLESDFQ-FEKLAKETEGYSGSDLKNLCIAAAYRPVQELLQ 940

  Fly   709 EQVKCLDISA---MRAITEQDFHSSLKRIRRSVA--PQSLNSYEKWSQDYGD 755
            |:.|.....|   :|:::..||..|..::..|||  ..::|...||::.||:
plant   941 EEQKGARAEASPGLRSLSLDDFIQSKAKVSPSVAYDATTMNELRKWNEQYGE 992

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	19/135 (14%)
		RecA-like_spastin	484..648	CDD:410932	91/166 (55%)
		AAA_lid_3	676..727	CDD:465537	21/53 (40%)
		Vps4_C	<722..754	CDD:462762	9/33 (27%)
AT1G50140	NP_175433.2	McrB	546..>770	CDD:441011	68/249 (27%)
		P-loop containing Nucleoside Triphosphate Hydrolases	715..881	CDD:476819	91/166 (55%)
		AAA_lid_3	905..941	CDD:465537	18/36 (50%)