DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spas and AT1G45000

DIOPT Version :9

Sequence 1:	NP_651206.3	Gene:	spas / 42846	FlyBaseID:	FBgn0039141	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_175120.1	Gene:	AT1G45000 / 841065	AraportID:	AT1G45000	Length:	399	Species:	Arabidopsis thaliana

Alignment Length:	490	Identity:	130/490 - (26%)
Similarity:	219/490 - (44%)	Gaps:	125/490 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   283 VWDRAQRL--HDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEE-----AQSKPQKTREP 340
            |.|..::|  |.::::.:..||:.|             |.:.||..|.|     .||..|...|
plant    15 VTDYRKKLLHHKELESRVRTARENL-------------RAAKKEFNKTEDDLKSLQSVGQIIGE- 65

  Fly   341 MLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSV 405
            :|..:.||  :|.|::|. ||:.....:......|||.|::..:::......:.|||.:
plant    66 VLRPLDNE--RLIVKASS-GPRYVVGCRSKVDKEKLTSGTRVVLDMTTLTIMRALPREV------ 121

  Fly   406 GAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLIL 470
                                                           .|||             .
plant   122 -----------------------------------------------DPVV-------------Y 126

  Fly   471 DEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELF--TGLRAPAKGLLLFGPPGNGKTLLA 533
            :.:.|....:.::.:.|.....:.|:|.:.||.:.||||  .|:: |.||:||:||||.||||||
plant   127 NMLHEDPGNISYSAVGGLGDQIRELRESIELPLMNPELFLRVGIK-PPKGVLLYGPPGTGKTLLA 190

  Fly   534 RAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSL----LSERSSS 594
            ||:|:...|.||.:.::::..||:|:..:|:|.:|..||..||.|||:||:|::    .||.:|:
plant   191 RAIASNIDANFLKVVSSAIIDKYIGESARLIREMFNYAREHQPCIIFMDEIDAIGGRRFSEGTSA 255

  Fly   595 EHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRE 657
            :.|..|.| .|.|.:.||.   ....::.::.|||||..||.|.||  |..:::.:.||:||:|.
plant   256 DREIQRTL-MELLNQLDGF---DQLGKVKMIMATNRPDVLDPALLRPGRLDRKIEIPLPNEQSRM 316

  Fly   658 LLLN---RLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAM 719
            .:|.   ..:.|.|. :|.||   :.|:.:|::|:||..:..:|.:..||            :..
plant   317 EILKIHASGIAKHGE-IDYEA---IVKLGEGFNGADLRNICTEAGMFAIR------------AER 365

  Fly   720 RAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYG 754
            ..:..:||   :|.:|:....:.|.|...::.|:|
plant   366 DYVIHEDF---MKAVRKLSEAKKLESSSHYNADFG 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	7/26 (27%)
		P-loop_NTPase	482..>538	CDD:304359	27/57 (47%)
		AAA	515..652	CDD:214640	59/142 (42%)
		AAA	519..650	CDD:278434	55/136 (40%)
		Vps4_C	<722..754	CDD:286426	7/31 (23%)
AT1G45000	NP_175120.1	RPT1	17..390	CDD:224143	127/479 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910