Protein Alignment spas and PEX1

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_196464.2
• Gene: PEX1 / 830746
• AraportID: AT5G08470
• Length: 1130
• Species: Arabidopsis thaliana
• Alignment Length: 571
• Identity: 145/571 - (25%)
• Similarity: 233/571 - (40%)
• Gaps: 99/571 - (17%)

  Fly   219 PGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDV 283
            ||.|..:||      |.|.:|.          |..|:|           |...|.|.|.:   ..
plant   602 PGSGKTILA------RAAAKYF----------EEQKDL-----------LAHVILVSCST---LA 636

  Fly   284 WDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTR-EPMLAGMTN 347
            .::.|.:|..:.:.::...:....:.:.:   .:..:.......|..|:....|. ...|..:.:
plant   637 LEKVQHIHHVLSSVIAEGLEHAPSVIILD---DLDSIISSSSDTEGTQASVGVTMLTKFLTDVID 698

  Fly   348 EPMKLRVRSSGYGPKATTS------------------------AQPTASGRKLTIGSKRPVNLAV 388
            :..:.|..|.|.||.|..:                        |.|..|.|...:  |..:...:
plant   699 DYGEYRNSSCGIGPLAFVASVQSLEQIPQTLSSSGRFDFHVQLAAPATSERGAIL--KHEIQKRL 761

  Fly   389 ANKSQTLPRNLGSK-TSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGAS 452
            .:.|:.:..||.:| ....|...:.....|...|:      ||:.|.:.:.:..|......:.|.
plant   762 LDCSEDILLNLAAKCEGYDAYDLEILVDRAVHAAI------GRHLPLESNISKYNLVKEDFTRAM 820

  Fly   453 TPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAK 517
            ...|.|      .::.|.....||| ::.|.|:.|....|.|::||:.|||..|::|.  ::|.:
plant   821 HDFVPV------AMRDITKSASEGG-RLGWEDVGGVTDIKNAIKEMIELPSKFPKIFA--KSPLR 876

  Fly   518 ---GLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSII 579
               .:||:||||.|||.:..|.|..||..|:::....|.:||:|..|:.||.:|:.|....|.|:
plant   877 LRSNVLLYGPPGCGKTHIVGAAAAACSLRFISVKGPELLNKYIGASEQAVRDIFSKAAAAAPCIL 941

  Fly   580 FIDEVDSLLSERSSSEHEASRRLKTEFLVEFDG---LPGNPDGDRIVVLAATNRPQELDEAALR- 640
            |.||.||:..:|.......:.|:..:||.|.||   |.|      :.|.|||:||..||.|.||
plant   942 FFDEFDSIAPKRGHDNTGVTDRVVNQFLTELDGVEVLTG------VFVFAATSRPDLLDPALLRP 1000

  Fly   641 -RFTKRVYVSLPDEQTRELLLNRLLQK--QGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEP 702
             |..:.:....|....|..:|..|.:|  ....:|.|.   :|.:|:|:||:||.||..||.|..
plant  1001 GRLDRLLLCDFPSPPERLEILTVLSRKLLMADDIDLEP---IALMTEGFSGADLQALLSDAQLAA 1062

  Fly   703 IRE-LNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVA-PQSLNSYEKWSQ 751
            :.| ||.|...  :......||:....|...:.:.||: .:....|:.:||
plant  1063 VHEYLNREDKP--ETGTTPIITDPLLKSIASKTKPSVSETEKQKLYDIYSQ 1111

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	12/77 (16%)
		P-loop_NTPase	482..>538	CDD:304359	23/58 (40%)
		AAA	515..652	CDD:214640	52/144 (36%)
		AAA	519..650	CDD:278434	51/135 (38%)
		Vps4_C	<722..754	CDD:286426	8/31 (26%)
PEX1	NP_196464.2	PEX-1N	109..182	CDD:286361
		SpoVK	585..1104	CDD:223540	142/562 (25%)
		AAA	589..>635	CDD:99707	15/62 (24%)
		AAA	881..1010	CDD:278434	51/134 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900