DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spas and AT4G27680

DIOPT Version :9

Sequence 1:	NP_651206.3	Gene:	spas / 42846	FlyBaseID:	FBgn0039141	Length:	758	Species:	Drosophila melanogaster
Sequence 2:	NP_194498.1	Gene:	AT4G27680 / 828882	AraportID:	AT4G27680	Length:	398	Species:	Arabidopsis thaliana

Alignment Length:	370	Identity:	135/370 - (36%)
Similarity:	195/370 - (52%)	Gaps:	48/370 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   426 FSSGRNTPPQR--SRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQ 488
            |:..|:..|.|  |:..:.:..........|:|.....|..:.   .|.|......||:..|.|.
plant    28 FAGLRHLDPNREASKKALEHKKEISKRLGRPLVQTNPYEDVIA---CDVINPDHIDVEFGSIGGL 89

  Fly   489 DVAKQALQEMVILPSVRPELFT--GLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAAS 551
            :..||||.|:||||..|||||.  .|..|.||:||:||||.|||:||:|:|.|..|.|:|:..::
plant    90 ETIKQALYELVILPLKRPELFAYGKLLGPQKGVLLYGPPGTGKTMLAKAIAKESGAVFINVRVSN 154

  Fly   552 LTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGN 616
            |.||:.||.:|||.|:|::|..:||:|||||||:|.|.:|.|::|||...:||||:..:||...:
plant   155 LMSKWFGDAQKLVSAVFSLAYKLQPAIIFIDEVESFLGQRRSTDHEAMANMKTEFMALWDGFSTD 219

  Fly   617 PDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAK 681
            |.. |::||||||||.|||||.|||..:...:.:||.:.|..:|...|:.:....|.: ...:|:
plant   220 PHA-RVMVLAATNRPSELDEAILRRLPQAFEIGIPDRRERAEILKVTLKGERVEPDID-FDHIAR 282

  Fly   682 ITDGYSGSDLTALAKDAALEPIRELNVEQVK---CLD---------------------------- 715
            :.:||:|||:..|.|.||..||||:...:.|   |||
plant   283 LCEGYTGSDIFELCKKAAYFPIREILDAERKGKPCLDPRPLSQLDLEKVLATSKKTQVAAGEYSL 347

  Fly   716 ---ISAMRAITEQD-FHSSLKRIRRSVAPQSLN----SYEKWSQD 752
               .||.|...|.| ..:::..|.:.:..|.:|    |.:.|.:|
plant   348 SSQSSAWRGSREPDEVQAAISGISKLLVSQIINLQSESQDSWQRD 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		P-loop_NTPase	482..>538	CDD:304359	32/57 (56%)
		AAA	515..652	CDD:214640	71/136 (52%)
		AAA	519..650	CDD:278434	68/130 (52%)
		Vps4_C	<722..754	CDD:286426	8/36 (22%)
AT4G27680	NP_194498.1	RecA-like_ATAD1	85..250	CDD:410928	88/165 (53%)
AT4G27680	NP_194498.1	AAA_lid_3	274..310	CDD:407720	15/36 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810