Protein Alignment spas and AtCDC48B

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_190891.1
• Gene: AtCDC48B / 824489
• AraportID: AT3G53230
• Length: 815
• Species: Arabidopsis thaliana
• Alignment Length: 617
• Identity: 164/617 - (26%)
• Similarity: 253/617 - (41%)
• Gaps: 146/617 - (23%)

  Fly   197 PQRFRPIQPLEMAANRPGGGY----SPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELA 257
            ||.|:.|      ..:|..|.    .||.|..|:|:...:...||.:.....:|..:..|..|..
plant   231 PQLFKSI------GVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESN 289

  Fly   258 IELYRKGIKELE------------DGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLAL 310
            :   ||..:|.|            |.||.......|:|   .:|:..::.|.:...:.|.|.:.:
plant   290 L---RKAFEEAEKNAPSIIFIDEIDSIAPKREKTHGEV---ERRIVSQLLTLMDGLKSRAHVIVM 348

  Fly   311 REQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKL--RVRSSGYGPKATTSAQPTASG 373
                                             |.||.|..:  .:|..|...:......|...|
plant   349 ---------------------------------GATNRPNSIDPALRRFGRFDREIDIGVPDEIG 380

  Fly   374 RKLTIGSKRPVNLAVANKSQTLPRNLG----SKTSVGAVQRQPAK--TAATPPAVRRQFS----- 427
            | |.:       |.:..|:..|..::.    ||.:.|.|....|.  |.|....:|.:..
plant   381 R-LEV-------LRIHTKNMKLAEDVDLERVSKDTHGYVGADLAALCTEAALQCIREKMDVIDLD 437

  Fly   428 ---------SGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWT 483
                     :.........:|.:.|:.||.                     |.|.|.....|.|.
plant   438 DEEIDAEILNSMAVSNDHFQTALGNSNPSA---------------------LRETVVEVPNVSWE 481

  Fly   484 DIAGQDVAKQALQEMVILPSVRPELFT--GLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLN 546
            ||.|.:..|:.|||.|..|...||.|.  |: :|:||:|.:||||.||||||:|:|.||.|.|::
plant   482 DIGGLENVKRELQETVQYPVEHPEKFEKFGM-SPSKGVLFYGPPGCGKTLLAKAIANECQANFIS 545

  Fly   547 ISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHE---ASRRLKTEFLV 608
            |....|.:.:.|:.|..||.:|..||...|.::|.||:||:.::|.:|..:   |:.|:..:.|.
plant   546 IKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQRGNSVGDAGGAADRVLNQLLT 610

  Fly   609 EFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRELLLNRLLQKQGSPL 671
            |.||:...   ..:.::.|||||..:|.|.||  |..:.:|:.||||::|..:....|:|.....
plant   611 EMDGMNAK---KTVFIIGATNRPDIIDPALLRPGRLDQLIYIPLPDEESRYQIFKSCLRKSPVAK 672

  Fly   672 DTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMR-------AITEQD--- 726
            |.: ||.|||.|.|:||:|:|.:.:.:....||| |:|:    ||...|       |:.|.:
plant   673 DVD-LRALAKYTQGFSGADITEICQRSCKYAIRE-NIEK----DIEKERKRAESPEAMEEDEEEI 731

  Fly   727 -------FHSSLKRIRRSVAPQSLNSYEKWSQ 751
                   |..|:|..||||:...:..|:.::|
plant   732 AEIKAGHFEESMKYARRSVSDADIRKYQAFAQ 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	18/89 (20%)
		P-loop_NTPase	482..>538	CDD:304359	29/57 (51%)
		AAA	515..652	CDD:214640	55/141 (39%)
		AAA	519..650	CDD:278434	51/135 (38%)
		Vps4_C	<722..754	CDD:286426	10/40 (25%)
AtCDC48B	NP_190891.1	CDC48	30..767	CDD:273521	164/617 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810