Protein Alignment spas and AT3G19740

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_188608.4
• Gene: AT3G19740 / 821511
• AraportID: AT3G19740
• Length: 993
• Species: Arabidopsis thaliana
• Alignment Length: 863
• Identity: 230/863 - (26%)
• Similarity: 364/863 - (42%)
• Gaps: 189/863 - (21%)

  Fly     2 VRTKNQSSSSSASSSSTKSPIKSSSGAGSSGGGLGGRQSTHRSSSASNVAAVVAGGSSAA----G 62
            :|.||.:|...|...|:...|...|..|:.   |...:.....:....|..:|...|..|    .
plant   200 IRQKNAASIYGARLDSSSGRILLQSVPGTE---LYRERLVRALARDVQVPLLVLDSSVLAPYDFA 261

  Fly    63 GGSSSNRRSPGSSPDGDDDTTTTDDLTPTTCSPRSGHHHSYGGYSSSVHKQNLYVVSFPIIFLFN 127
            ...:....|.|.:.:.:.|.:||:.......|.:|..........|...:..|.|..       .
plant   262 DDYNEESESDGENAEAEADESTTESDAEEDSSAQSEEDSEAKADGSDSEEACLEVSE-------E 319

  Fly   128 VLRSLIYQL----FCIFRYLYGASTKVIYRPHRRDCNIEIVVQNSSKEQQQSLN-------HPSE 181
            .::.::.:|    ..:...|:|.:.:.            ..|::|.|.::.:..       .||
plant   320 AIKKIVPKLEEFEKLVAEELHGEACEA------------AAVEHSDKARRPAKKGDRVKYVGPS- 371

  Fly   182 LNREGDGQEQQLSNQPQRFRPIQPLEMAANRP------GGGYSPGPGDPLLAKQKHHHRRAFEYI 240
              ::.|.:.:.||:..:.    :..|:..||.      ||..|...||.  ...:|.|:....:|
plant   372 --KKADAKHRPLSSGQRG----EVYEVNGNRVAVIFDIGGDTSSEGGDK--KSTEHSHKLHMHWI 428

  Fly   241 SKA-LKID---EENEGHKELAIELYRKGIKELEDGIAV----DCW-------SGRGDVWDRAQRL 290
            ... ||.|   :..:|:  :|:|...:.:...:..|..    ..|       |.:.:..|:.|.:
plant   429 DVGDLKHDLDMQAEDGY--IALEALSEVLHSTQPLIVYFPDSSQWLSRAVPKSKQNEFVDKVQEM 491

  Fly   291 HDKMQTNLSM----------ARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGM 345
            .||:.:.:.|          :::|..|..:.....::.:|.|..|:..|..: .:||.|
plant   492 FDKLSSPVVMICGRNKIETGSKEREKFTMILPNFGRLAKLPLPLKRLTEGLT-GRKTSE------ 549

  Fly   346 TNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANK------------------- 391
            .||..||........|                  .|...||.|.||
plant   550 DNEIYKLFTNVMNLVP------------------PKEEENLIVFNKQLGEDRRIVMSRSNLNELL 596

  Fly   392 -----SQTLPRNLGSKTSVGAV-QRQPAK-----------TAATPPAVRRQFSSGRNTPPQRSRT 439
                 ::.|..:|....:.|.: .:|.|:           ::...|:::    .||...|:.|..
plant   597 KALEENELLCTDLYQVNTDGVILTKQRAEKVIGWARNHYLSSCPSPSIK----EGRLILPRESIE 657

  Fly   440 PINNNGPSGSGASTPVVSVKGVE----------QKLVQLILDE---------IVEGGAKVEWTDI 485
                            :|||.::          |.|..:..||         :..|...|::.||
plant   658 ----------------ISVKRLKAQEDISRKPTQNLKNIAKDEFETNFVSAVVAPGEIGVKFDDI 706

  Fly   486 AGQDVAKQALQEMVILPSVRPELFT--GLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNIS 548
            ...:..|:.|.|:||||..||||||  .|..|.||:|||||||.||||||:|:|||..|.|::|:
plant   707 GALEHVKKTLNELVILPMRRPELFTRGNLLRPCKGILLFGPPGTGKTLLAKALATEAGANFISIT 771

  Fly   549 AASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSS-EHEASRRLKTEFLVEFDG 612
            .::||||:.||.|||.:|||:.|..:.|.|||:|||||||..|..: ||||:||::.||:..:||
plant   772 GSTLTSKWFGDAEKLTKALFSFASKLAPVIIFVDEVDSLLGARGGAFEHEATRRMRNEFMAAWDG 836

  Fly   613 LPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALR 677
            | .:.|..||::|.|||||.:||:|.:||..:|:||.|||.:.|..:|...|..:......| ..
plant   837 L-RSKDSQRILILGATNRPFDLDDAVIRRLPRRIYVDLPDAENRLKILKIFLTPENLETGFE-FD 899

  Fly   678 RLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISA---MRAITEQDFHSSLKRIRRSVA 739
            :|||.|:|||||||..|...||..|::||..|:.|....:|   :|.::..||..|..::..|||
plant   900 KLAKETEGYSGSDLKNLCIAAAYRPVQELLQEENKDSVTNASPDLRPLSLDDFIQSKAKVSPSVA 964

  Fly   740 --PQSLNSYEKWSQDYGD 755
              ..::|...||::.||:
plant   965 YDATTMNELRKWNEQYGE 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	18/102 (18%)
		RecA-like_spastin	484..648	CDD:410932	90/166 (54%)
		AAA_lid_3	676..727	CDD:465537	21/53 (40%)
		Vps4_C	<722..754	CDD:462762	9/33 (27%)
AT3G19740	NP_188608.4	tolA	<266..>377	CDD:236545	19/132 (14%)
		CDC48	<582..981	CDD:273521	148/420 (35%)
		P-loop containing Nucleoside Triphosphate Hydrolases	705..871	CDD:476819	90/166 (54%)