Protein Alignment spas and CDC48

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_187595.1
• Gene: CDC48 / 820142
• AraportID: AT3G09840
• Length: 809
• Species: Arabidopsis thaliana
• Alignment Length: 620
• Identity: 160/620 - (25%)
• Similarity: 248/620 - (40%)
• Gaps: 150/620 - (24%)

  Fly   197 PQRFRPIQPLEMAANRPGGGY----SPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELA 257
            ||.|:.|      ..:|..|.    .||.|..|:|:...:...||.:.....:|..:..|..|..
plant   230 PQLFKSI------GVKPPKGILLYGPPGSGKTLIARAVANETGAFFFCINGPEIMSKLAGESESN 288

  Fly   258 IELYRKGIKELE------------DGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLAL 310
            :   ||..:|.|            |.||.......|:|   .:|:..::.|.:...:.|.|.:.:
plant   289 L---RKAFEEAEKNAPSIIFIDEIDSIAPKREKTNGEV---ERRIVSQLLTLMDGLKSRAHVIVM 347

  Fly   311 REQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKL--RVRSSGYGPKATTSAQPTASG 373
                                             |.||.|..:  .:|..|...:......|...|
plant   348 ---------------------------------GATNRPNSIDPALRRFGRFDREIDIGVPDEIG 379

  Fly   374 RKLTIGSKRPVNLAVANKSQTLPRNLG----SKTSVGAVQRQPAK--TAATPPAVRRQFS----- 427
            | |.:       |.:..|:..|..::.    ||.:.|.|....|.  |.|....:|.:..
plant   380 R-LEV-------LRIHTKNMKLAEDVDLERISKDTHGYVGADLAALCTEAALQCIREKMDVIDLE 436

  Fly   428 ---------SGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWT 483
                     :......:...|.:.|:.||.                     |.|.|.....|.|.
plant   437 DDSIDAEILNSMAVTNEHFHTALGNSNPSA---------------------LRETVVEVPNVSWN 480

  Fly   484 DIAGQDVAKQALQEMVILPSVRPELFT--GLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLN 546
            ||.|.:..|:.|||.|..|...||.|.  |: :|:||:|.:||||.||||||:|:|.||.|.|::
plant   481 DIGGLENVKRELQETVQYPVEHPEKFEKFGM-SPSKGVLFYGPPGCGKTLLAKAIANECQANFIS 544

  Fly   547 ISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSE----HEASRRLKTEFL 607
            :....|.:.:.|:.|..||.:|..||...|.::|.||:||:.::|....    ..|:.|:..:.|
plant   545 VKGPELLTMWFGESEANVREIFDKARQSAPCVLFFDELDSIATQRGGGSGGDGGGAADRVLNQLL 609

  Fly   608 VEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRELLLNRLLQKQGSP 670
            .|.||:...   ..:.::.|||||..:|.|.||  |..:.:|:.||||.:|..:....|:|  ||
plant   610 TEMDGMNAK---KTVFIIGATNRPDIIDSALLRPGRLDQLIYIPLPDEDSRLNIFKAALRK--SP 669

  Fly   671 LDTEA-LRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQ--------- 725
            :..:. :..|||.|.|:||:|:|.:.:.|....||| |:|:    ||...:..:|.
plant   670 IAKDVDIGALAKYTQGFSGADITEICQRACKYAIRE-NIEK----DIEKEKRRSENPEAMEEDGV 729

  Fly   726 ---------DFHSSLKRIRRSVAPQSLNSYEKWSQ 751
                     .|..|:|..||||:...:..|:.::|
plant   730 DEVSEIKAAHFEESMKYARRSVSDADIRKYQAFAQ 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	18/89 (20%)
		RecA-like_spastin	484..648	CDD:410932	64/171 (37%)
		AAA_lid_3	676..727	CDD:465537	18/68 (26%)
		Vps4_C	<722..754	CDD:462762	10/48 (21%)
CDC48	NP_187595.1	CDC48	29..768	CDD:273521	160/620 (26%)