Protein Alignment spas and CDC48B

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_178463.1
• Gene: CDC48B / 814895
• AraportID: AT2G03670
• Length: 603
• Species: Arabidopsis thaliana
• Alignment Length: 552
• Identity: 143/552 - (25%)
• Similarity: 222/552 - (40%)
• Gaps: 148/552 - (26%)

  Fly   324 EKQKEEAQSKPQKTREPMLAGMTNEPMK--LRVRSSG---------YGPKAT--TS---AQPTAS 372
            ||.:.||:....:.....|..:...|.:  |..|:.|         |||..|  ||   |.....
plant    16 EKWRAEAEIGGNERALQALRELIIFPFRYPLEARTLGLKWPRGLLLYGPPGTGKTSLVRAVVQEC 80

  Fly   373 GRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPA------------------------ 413
            ...|.:.|...|:.|.|.:|:.:.|...::.|..||..:|:
plant    81 DAHLIVLSPHSVHRAHAGESEKVLREAFAEASSHAVSDKPSVIFIDEIDVLCPRRDARREQDVRI 145

  Fly   414 ---------------------------KTAATPPAVRRQFSSGR-------NTPPQRSR------ 438
                                       :..|..||:||   :||       :||.:..|
plant   146 ASQLFTLMDSNKPSSSAPRVVVVASTNRVDAIDPALRR---AGRFDALVEVSTPNEEDRLKILQL 207

  Fly   439 ---------------TPINNNG--------------PSGSGASTPVVSVKGVEQKLVQLILDEIV 474
                           ..|:.||              .|.|..|:..:.:...:.|:.:.::...:
plant   208 YTKKVNLDPSVDLQAIAISCNGYVGADLEALCREATISASKRSSDSLILTSQDFKIAKSVVGPSI 272

  Fly   475 EGG-----AKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLR-APAKGLLLFGPPGNGKTLLA 533
            ..|     .||.|.|:.|....|:.||:.|..|......|..:. :|.:|:||.||||..||.||
plant   273 NRGITVEIPKVTWDDVGGLKDLKKKLQQAVEWPIKHSAAFVKMGISPMRGILLHGPPGCSKTTLA 337

  Fly   534 RAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSER----SSS 594
            :|.|....|:|.::|.|.|.|.|||:||.|:|..|..||...|||||.||.|.:..:|    ||:
plant   338 KAAANAAQASFFSLSCAELFSMYVGEGEALLRNTFQRARLASPSIIFFDEADVVACKRGDESSSN 402

  Fly   595 EHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRE 657
            ......||.:..|.|.|||   .:...|:||||||||..:|.|.:|  ||...:||..||.:.|.
plant   403 SSTVGERLLSTLLTEMDGL---EEAKGILVLAATNRPYAIDAALMRPGRFDLVLYVPPPDLEARF 464

  Fly   658 LLL-----NRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDIS 717
            .:|     |..|   |..:|   ||::|:.||.::|::|..|.:::....:|| |:
plant   465 EILQVHTRNMTL---GDDVD---LRKIAEETDLFTGAELEGLCRESGTVSLRE-NI--------- 513

  Fly   718 AMRAITEQDFHSSLKRIRRSVAPQSLNSYEKW 749
            |..|:..:.|.::...::.::..:.:.:|..:
plant   514 AATAVFNRHFQTAKSSLKPALTIEEVETYSSF 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		P-loop_NTPase	482..>538	CDD:304359	22/56 (39%)
		AAA	515..652	CDD:214640	64/142 (45%)
		AAA	519..650	CDD:278434	62/136 (46%)
		Vps4_C	<722..754	CDD:286426	2/28 (7%)
CDC48B	NP_178463.1	CDC48	<23..551	CDD:273521	139/545 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900