Protein Alignment spas and katna1

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001072433.1
• Gene: katna1 / 779887
• XenbaseID: XB-GENE-995720
• Length: 492
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 174/494 - (35%)
• Similarity: 257/494 - (52%)
• Gaps: 60/494 - (12%)

  Fly   288 QRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQS---------KPQKTREPMLA 343
            |.:.|:|...|...:|.  ||..:.|.: .|.::::.|..::..|         .|.||.:....
 Frog    30 QGVLDQMNKYLYSVKDT--FLQQKWQQV-WQEINMEAKHVKDIMSTLEGFKLDNSPVKTTQHEFP 91

  Fly   344 GMTNEPMKLRV---RSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSV 405
            ....|...|.|   |....||:...|.|..        .:|...|...|.|...||    |..:.
 Frog    92 AHDGEVWSLPVPVERRPSPGPRKRQSVQCN--------DNKSHNNRFGAGKGPNLP----SSKNT 144

  Fly   406 GAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVK-----GVEQKL 465
            ..|:.:|.:       .|.:..:......::::          |........||     |.::.|
 Frog   145 NNVKMKPVR-------AREKKDTFLKVKDEKNK----------SSVDVSETEVKKFDGTGYDKDL 192

  Fly   466 VQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKT 530
            ::.:..:|:.....:.|.|||..:.||:.|:|.|:||...||.|.|:|.|.||:|:.||||.|||
 Frog   193 IEALERDIISQNPNIRWDDIADLEEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKT 257

  Fly   531 LLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSER-SSS 594
            |||:||||||..||.|||:::|||||.|:.|||||.||.:||...|:.|||||:||:.|.| :|.
 Frog   258 LLAKAVATECKTTFFNISSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSE 322

  Fly   595 EHEASRRLKTEFLVEFDGLPG---NPDGDRIV-VLAATNRPQELDEAALRRFTKRVYVSLPDEQT 655
            |||||||:|.|.||:.||:.|   |.|..::| ||||||.|.::|||..||..||:|:.||..:.
 Frog   323 EHEASRRVKAELLVQMDGVGGASENEDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKG 387

  Fly   656 RELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRE----LNVEQVKCLDI 716
            ||.|| |:..|:....|...:..:|:..|||||:|:|.:.:||:|..:|.    |..|:::.|..
 Frog   388 REELL-RINLKELELADDVNIECIAENMDGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLSR 451

  Fly   717 SAMR-AITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYG 754
            ..|. ..|.:||..:||::.:||:...:..||||.:::|
 Frog   452 DDMHMPTTMEDFEMALKKVSKSVSASDIEKYEKWIEEFG 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	5/19 (26%)
		RecA-like_spastin	484..648	CDD:410932	97/168 (58%)
		AAA_lid_3	676..727	CDD:465537	17/55 (31%)
		Vps4_C	<722..754	CDD:462762	11/31 (35%)
katna1	NP_001072433.1	Kp60-NTD	5..72	CDD:439297	10/44 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..158		18/85 (21%)
		RecA-like_KTNA1	211..380	CDD:410930	97/168 (58%)
		AAA_lid_3	404..448	CDD:465537	14/43 (33%)
		Vps4_C	<452..490	CDD:462762	12/37 (32%)