Protein Alignment spas and Pex1

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001280735.1
• Gene: Pex1 / 71382
• MGIID: 1918632
• Length: 1284
• Species: Mus musculus
• Alignment Length: 228
• Identity: 87/228 - (38%)
• Similarity: 126/228 - (55%)
• Gaps: 11/228 - (4%)

  Fly   482 WTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAK---GLLLFGPPGNGKTLLARAVATECSAT 543
            |..|.|....:|.|.:.:.||:..||||..|  |.:   |:||:||||.||||||..||.|....
Mouse   840 WDKIGGLHEVRQILMDTIQLPAKYPELFANL--PIRQRTGILLYGPPGTGKTLLAGVVARESGMN 902

  Fly   544 FLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLV 608
            |::|....|.|||:|..|:.||.:|..|:..:|.|:|.||.:|:...|.......:.|:..:.|.
Mouse   903 FISIKGPELLSKYIGASEQAVRDVFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLT 967

  Fly   609 EFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRELLLNRLLQKQGSPL 671
            :.||:.|.   ..:.|||||:||..:|.|.||  |..|.||...||:.:|..:|. :|.|..:..
Mouse   968 QLDGVEGL---QGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEILT-VLSKSLALA 1028

  Fly   672 DTEALRRLAKITDGYSGSDLTALAKDAALEPIR 704
            |...|:.:|.:||.::|:||.||..:|.||.::
Mouse  1029 DDVDLQHVASVTDSFTGADLKALLYNAQLEALQ 1061

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		RecA-like_spastin	484..648	CDD:410932	66/168 (39%)
		AAA_lid_3	676..727	CDD:465537	12/29 (41%)
		Vps4_C	<722..754	CDD:462762
Pex1	NP_001280735.1	PEX-2N	17..98	CDD:462730
		PEX-1N	104..179	CDD:462729
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	339..373
		CDC48	<596..1061	CDD:273521	87/226 (38%)
		RecA-like_PEX1_r2	849..1006	CDD:410934	64/161 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1261..1284