Protein Alignment spas and Fignl2

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001201840.1
• Gene: Fignl2 / 668225
• MGIID: 3646919
• Length: 644
• Species: Mus musculus
• Alignment Length: 477
• Identity: 139/477 - (29%)
• Similarity: 201/477 - (42%)
• Gaps: 108/477 - (22%)

  Fly   358 GYGPKATTSAQPTAS-GRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSV---------------- 405
            ||||.|.....|.|. ..:...|:..|   ..|..:..||..|.:.|.:
Mouse   193 GYGPSAPLYNYPAAGYAAQPGYGALPP---PAAPPAPYLPSGLAAPTPLPAPAPPRPAPYGFPAA 254

  Fly   406 -------------GAVQR------QPAKT----AATPPAVRRQFSSG---RNTPPQRS------- 437
                         ||..|      :|||.    .|:.||.......|   |:.||..:
Mouse   255 AEGVSLKRKAVDEGAEARYRKYAYEPAKAPAADGASYPAADDTECRGNGFRSKPPGATEDGTGKY 319

  Fly   438 --------------------------RTPINNNG---PSGSGASTPVVSVKGVEQKLVQLILDEI 473
                                      |.|..:.|   |||..|       |||:...::|:..::
Mouse   320 GGGGPLKVLGSPAYAPQLEPFDKFPERVPAAHGGFAEPSGEPA-------KGVDPGALELVSSKM 377

  Fly   474 VEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVAT 538
            |:.|..|:|.|:|||...|.||:|.::.|.:||....|...|.:.:|.|||.|.||.||.|.:||
Mouse   378 VDCGPPVQWADVAGQGALKAALEEELLWPLLRPPACPGSALPPRTVLFFGPRGCGKALLGRCLAT 442

  Fly   539 ECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLK 603
            ...||.|.:..|.|.:....:|.:|::|.||.||...|:::.|.|:|:||..|...   ||  |:
Mouse   443 RLGATLLRLRGAGLAASGAVEGARLLQAAFAAARCRPPAVLLISELDALLPARDDG---AS--LR 502

  Fly   604 TEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQG 668
            ...|...||..| ...|.::|:..|:||..||||..|||..|.||:|||...|..:|.|.|.:||
Mouse   503 APLLTCLDGSCG-ARADGVLVVGTTSRPAALDEATRRRFALRFYVALPDGAARGQILQRALAQQG 566

  Fly   669 SPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAM-RAITEQDFHSSLK 732
            ..|:...|..|.:.|.|:||.:|..|.:.||.|            ..||.: |.::.:|..::|.
Mouse   567 CALNERELAALVQGTQGFSGGELGQLCQQAAAE------------AGISGLQRPLSYKDVEAALA 619

  Fly   733 RIRRSVAPQSLNSYEKWSQDYG 754
            ::......:.|:|..:|.:.||
Mouse   620 KVGSRAPSKELDSLVEWDKMYG 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		P-loop_NTPase	482..>538	CDD:304359	24/55 (44%)
		AAA	515..652	CDD:214640	55/136 (40%)
		AAA	519..650	CDD:278434	53/130 (41%)
		Vps4_C	<722..754	CDD:286426	5/31 (16%)
Fignl2	NP_001201840.1	SpoVK	<381..638	CDD:223540	98/274 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810