Protein Alignment spas and zgc:153738

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001073437.3
• Gene: zgc:153738 / 558115
• ZFINID: ZDB-GENE-061013-622
• Length: 818
• Species: Danio rerio
• Alignment Length: 637
• Identity: 130/637 - (20%)
• Similarity: 229/637 - (35%)
• Gaps: 184/637 - (28%)

  Fly   162 EIVVQNS-----------SKEQQQSLNHPSELNREGDGQEQQLSNQPQRFRPIQPLEMAANRPGG 215
            |::.||:           ..:.|:|:.......||.:|.|.:.:.:.|    |:...:......|
Zfish   251 ELIAQNNKALRRTRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQ----IRQWFIECRDATG 311

  Fly   216 GYSPGP-----GDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKG---IKELEDGI 272
            .:...|     |..|:..:|.....|.|..:|..:...:|...||...|..:||   .:|.|.|:
Zfish   312 SFPDYPEEEDGGSALIFAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGL 376

  Fly   273 AV-----------------DCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRL 320
            .:                 :.|..|.:..:.:||                |.|.|.::|
Zfish   377 KMLPSACLPDLERSHKTYSEVWKNRNESKNFSQR----------------HELELIKED------ 419

  Fly   321 SLKEKQKEEAQSKPQKTREPMLAGMTNEPMKL------RVRSSGYGPKATTSAQPTASGRKLTIG 379
                |:||......::..|.|...:.|..:.:      :|:.:....||:.||:.....:.||..
Zfish   420 ----KRKEIEVEIRKQVDELMRQELANWKLAVDKEKSGKVKGAAKKKKASKSAKRKKKDKDLTAD 480

  Fly   380 S---------------KRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSG 429
            .               |:|.|:       .|...||..:.:|...||
Zfish   481 RTTESLFEELVEQELLKKPENV-------KLKDYLGDYSYLGTTLRQ------------------ 520

  Fly   430 RNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQA 494
                                ....|:.|:..|.|.:.   |..|:..|:              ||
Zfish   521 --------------------SDIEPMPSLSDVRQVVA---LYAILPLGS--------------QA 548

  Fly   495 LQEMVILPSVRPELFTGLRAP-AKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVG 558
            :.|               ::| .|.:||.||.|.||.:|..|:..|..|...::|..::..||.|
Zfish   549 VHE---------------KSPLVKTILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPG 598

  Fly   559 DG--EKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEA--SRRLKTEFLVEFDGLPGNPDG 619
            ..  :.::..:|.|||.||||:|:|.:.:.:...:...|.:.  .:|||.:.......:.|.
Zfish   599 RNGLQMMLHLVFKVARLMQPSVIWIGDAEKMFYRKVPKEEKELDPKRLKKDLPKILKSIRGE--- 660

  Fly   620 DRIVVLAATNRPQELDEAALRRF-TKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEA-LRRLAKI 682
            |.::::..|:.|...|..:|.:| .|.:.:..||..:|.::...|::|.|..:..:. |..||||
Zfish   661 DCVLIVGTTSDPHSADLKSLCKFYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKI 725

  Fly   683 TDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRI 734
            :|||:...:..:.:..    :.|..::|.      ..|.:|..:|.|.|.||
Zfish   726 SDGYTQGHMVQVVRSI----LTERRIQQF------PKRPLTASEFVSPLARI 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	18/97 (19%)
		RecA-like_spastin	484..648	CDD:410932	42/169 (25%)
		AAA_lid_3	676..727	CDD:465537	12/50 (24%)
		Vps4_C	<722..754	CDD:462762	6/13 (46%)
zgc:153738	NP_001073437.3	IQ	207..223	CDD:197470
		RecA-like_IQCA1	531..690	CDD:410914	47/193 (24%)