DRSC/TRiP Functional Genomics Resources

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Protein Alignment spas and nsfb

DIOPT Version :9

Sequence 1:NP_651206.3 Gene:spas / 42846 FlyBaseID:FBgn0039141 Length:758 Species:Drosophila melanogaster
Sequence 2:NP_001019625.2 Gene:nsfb / 554200 ZFINID:ZDB-GENE-050808-1 Length:747 Species:Danio rerio


Alignment Length:341 Identity:95/341 - (27%)
Similarity:152/341 - (44%) Gaps:68/341 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   459 KGVEQKLV--QLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLL 521
            ||..|.::  ....:.:..||...|::||     .::|....|..|.:..::  |.: ..||:||
Zfish   202 KGSRQSIINPDWNFERMGIGGLDKEFSDI-----FRRAFASRVFPPDIVEQM--GCK-HVKGILL 258

  Fly   522 FGPPGNGKTLLARAVATECSATFLN------ISAASLTSKYVGDGEKLVRALFAVARHMQP---- 576
            :||||.||||:||.:     ...||      ::...:.:||||:.|..:|.|||.|...|.    
Zfish   259 YGPPGCGKTLMARQI-----GKMLNAREPKVVNGPEILNKYVGESEANIRKLFADAEEEQKRLGA 318

  Fly   577 ----SIIFIDEVDSLLSER-----SSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQ 632
                .||..||:|::..:|     |:..|:.   :..:.|.:.||:   ...:.|:|:..||||.
Zfish   319 NSGLHIIIFDEIDAICKQRGSMAGSTGVHDT---VVNQLLSKIDGV---EQLNNILVIGMTNRPD 377

  Fly   633 ELDEAALR--RFTKRVYVSLPDEQTRELLLN--RLLQKQGSPLDTEA-LRRLAKITDGYSGSDLT 692
            .:|||.||  |...::.:.||||..|..:||  ....||.:.|..:. ::.||..|..|||::|.
Zfish   378 LIDEALLRPGRLEVKMEIGLPDETGRVQILNIHTAKMKQSNMLAKDVDVKELAVETKNYSGAELE 442

  Fly   693 ALAKDAALEPIR---------ELNVEQVKCLDISAMRAITEQDFHSSLKR--------IRRSVAP 740
            .|.:.|....:.         |::.|:.:.|.:|      ..||.:||..        .:...:.
Zfish   443 GLVRAAQSTAMNRHIKATTQVEVDTEKAQTLQVS------RSDFLASLNNDIKPAFGSNQEDYSS 501

  Fly   741 QSLNSYEKWSQDYGDI 756
            ..:|...|||....||
Zfish   502 YIMNGIVKWSNAVSDI 517

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spasNP_651206.3 MIT_spastin 230..308 CDD:239142
P-loop_NTPase 482..>538 CDD:304359 20/55 (36%)
AAA 515..652 CDD:214640 51/157 (32%)
AAA 519..650 CDD:278434 48/151 (32%)
Vps4_C <722..754 CDD:286426 8/39 (21%)
nsfbNP_001019625.2 CDC48_N 5..85 CDD:308138
CDC48_2 111..183 CDD:215011
SpoVK <220..490 CDD:223540 86/294 (29%)
AAA 538..670 CDD:214640
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0464
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
21.900

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