Protein Alignment spas and Rpt6R

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_651811.1
• Gene: Rpt6R / 43635
• FlyBaseID: FBgn0039788
• Length: 399
• Species: Drosophila melanogaster
• Alignment Length: 524
• Identity: 140/524 - (26%)
• Similarity: 228/524 - (43%)
• Gaps: 140/524 - (26%)

  Fly   240 ISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDR 304
            :||.:.|.|.:||..    ..|.:.|.||:..:                   ::.|.||
  Fly     1 MSKDVGIPEGSEGFH----SYYTQKISELQFTV-------------------NERQKNL------ 36

  Fly   305 LHFLALREQDLQMQR--LSLKEK-QKEEAQSKPQKTR--EPMLAGMTNEPMKLRVRSSGYGPKAT 364
                 ||   ||.||  |:||.: .:||.|...::..  ..::..|....:.::|...|   |..
  Fly    37 -----LR---LQAQRNELNLKVRLLREELQLLQEQGSYIAEVVKPMDKNKVLVKVHPEG---KYV 90

  Fly   365 TSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSG 429
            .....|.:.:.:|..|:    :|:.|:|.||.:.|.:|..
  Fly    91 VDVDKTINIKDVTPSSR----VALRNESYTLHKILPNKVD------------------------- 126

  Fly   430 RNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQA 494
                                    |:||:     .||:.:.|...|        .:.|.|...|.
  Fly   127 ------------------------PLVSL-----MLVEKVPDSTYE--------MVGGLDKQIQE 154

  Fly   495 LQEMVILPSVRPELF--TGLRAPAKGLLLFGPPGNGKTLLARAVA--TECSATFLNISAASLTSK 555
            ::|::.||...||||  .|:..| ||:||:||||.||||||||||  |||  ||:.:|.:.|..|
  Fly   155 IKEVIELPVKHPELFDALGITQP-KGVLLYGPPGTGKTLLARAVAHHTEC--TFIRVSGSELVQK 216

  Fly   556 YVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLS---ERSSSEHEASRRLKTEFLVEFDGLPGNP 617
            ::|:|.::||.||.:||...|||||:||:||:.|   |..:.:.|..|.: .|.|.:.||.....
  Fly   217 FIGEGSRMVRELFVMAREHAPSIIFMDEIDSIGSARLETGTGDSEVQRTM-LELLNQLDGFEATK 280

  Fly   618 DGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLA 680
            :   |.|:.||||...||:|.||  |..:::....|:|:.|..:|....:|........ ||::|
  Fly   281 N---IKVIMATNRIDVLDQALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGIN-LRKIA 341

  Fly   681 KITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNS 745
            :...|.||:::..:..:|.:..:||..|.            :|::||..::.::....:.::::.
  Fly   342 EEMPGASGAEVKGVCTEAGMYALRERRVH------------VTQEDFEMAVSKVMMKDSEKNMSI 394

  Fly   746 YEKW 749
            .:.|
  Fly   395 RKFW 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	13/67 (19%)
		P-loop_NTPase	482..>538	CDD:304359	30/59 (51%)
		AAA	515..652	CDD:214640	64/143 (45%)
		AAA	519..650	CDD:278434	61/137 (45%)
		Vps4_C	<722..754	CDD:286426	4/28 (14%)
Rpt6R	NP_651811.1	RPT1	3..396	CDD:224143	138/518 (27%)
		AAA	180..311	CDD:278434	61/136 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910