Protein Alignment spas and CG12010

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_728878.1
• Gene: CG12010 / 38421
• FlyBaseID: FBgn0035443
• Length: 717
• Species: Drosophila melanogaster
• Alignment Length: 613
• Identity: 161/613 - (26%)
• Similarity: 242/613 - (39%)
• Gaps: 152/613 - (24%)

  Fly   197 PQRF-RPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIEL 260
            |..| ||::.||....              .:|....||    :.:.||.:...:.|...|..|.
  Fly   194 PHSFERPMEQLEKLLE--------------TSKISFSHR----FPTTALVVGPVDCGKSGLLSEF 240

  Fly   261 YRKGIKELEDGIAVDCW---------SGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQ 316
            .|:.        :.:|:         |..|:..:..:|:....||.....|..|..:.|.| ||:
  Fly   241 LRRH--------SCNCFYITASQVLRSYPGETEEELRRIFQAAQTFKEKLRPLLPIVILIE-DLE 296

  Fly   317 MQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKLRVRSSGYG-----PKA----TTSAQPTAS 372
            :...|                  ..:|...|....||:.:..|.     |:.    .||..|.:.
  Fly   297 LLCPS------------------TAVADAKNSSNSLRISAELYKLLDALPRGIICLATSGVPDSL 343

  Fly   373 G--------RKLTI-----GSKRPV-----NLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATP 419
            .        |::||     |.:|.:     .:...|.||||..::...|....:    |......
  Fly   344 HEHARRRFVREVTINMPSEGQRRQLVEHLCEVHELNISQTLLEHIARNTQGYVI----ADLTLLL 404

  Fly   420 PAVRRQ-------------FSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILD 471
            ..|::|             ..|...|.|..||             ||.|...|
  Fly   405 RRVQQQLLTKDDFDIEHIFLKSLSQTQPSASR-------------STDVRVSK------------ 444

  Fly   472 EIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFT--GLRAPAKGLLLFGPPGNGKTLLAR 534
              :..|.:|    |.|.:..|:.||..|:....:...|.  ||..| ||:||:||||..||.:|:
  Fly   445 --MTAGFEV----IGGMEALKRTLQVSVLAGIRQSAAFARFGLSLP-KGVLLYGPPGCAKTTVAK 502

  Fly   535 AVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSE---- 595
            .:|.|...||:..|||.:.|.|||..|:.:..:|..||...|.:||:||:|||:..|:.|.
  Fly   503 CLAKEADMTFIATSAAEVYSPYVGCAERFISRIFDTARKNAPCLIFLDEIDSLVGRRTVSSGGGG 567

  Fly   596 HEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTREL 658
            .:...|:.:..|.|.:|:.|......|:|:||||||..:|:|.||  ||.|.::|..|||::|..
  Fly   568 GQVQLRILSTLLTEMNGIVGGGSQQHILVVAATNRPDMIDDALLRPGRFDKLIHVPAPDEKSRLA 632

  Fly   659 LLNRLLQKQGSPL-DTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAI 722
            ||.  |..|..|. :...|:.:|..||.|||:||..|..:||:|..:.         |..|.. |
  Fly   633 LLK--LHSQRMPFHENVFLQEIAARTDRYSGADLCNLCNEAAIEAFQR---------DFKATE-I 685

  Fly   723 TEQDFHSSLKRIRRSVAPQSLNSYEKWS 750
            ..|||...|.:.:.|:....::.|.|::
  Fly   686 ELQDFEKVLTKQKSSLTQSQIDGYYKFA 713

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	16/86 (19%)
		P-loop_NTPase	482..>538	CDD:304359	21/57 (37%)
		AAA	515..652	CDD:214640	58/142 (41%)
		AAA	519..650	CDD:278434	55/136 (40%)
		Vps4_C	<722..754	CDD:286426	8/29 (28%)
CG12010	NP_728878.1	SpoVK	201..707	CDD:223540	155/598 (26%)
		AAA	224..357	CDD:278434	28/159 (18%)
		AAA	487..623	CDD:278434	54/135 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900