Protein Alignment spas and CG5776

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001260420.1
• Gene: CG5776 / 34680
• FlyBaseID: FBgn0032450
• Length: 799
• Species: Drosophila melanogaster
• Alignment Length: 556
• Identity: 145/556 - (26%)
• Similarity: 239/556 - (42%)
• Gaps: 138/556 - (24%)

  Fly   247 DEENEGHKEL----AIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHF 307
            :|.::||.:|    :.|:|.|.:.|.|..:        |.:::||.. |....|.|.:  :.:|.
  Fly   329 EERSQGHVQLIRINSGEVYSKFLGETEQKL--------GAIFERAYN-HYPHPTLLLI--EDVHN 382

  Fly   308 LALREQDLQMQR------LSLKEKQKEEAQSKPQKTREPMLAGMTN-EPMKLRVRSSGYGPKATT 365
            |..::::..:.:      |||.::....:|.|..||.  :||..:. :.:...:|.:|.......
  Fly   383 LCPKQENSDLVKRVSLAFLSLLDQLSSPSQLKGSKTF--VLATSSQIDTLHPSIRRAGRLDNEVE 445

  Fly   366 SAQPTASGR------------------------KLTIG--SKRPVNLAVANKSQTLPRNLGSKTS 404
            ...|::..|                        .:|.|  .....||..|...|..|..|...
  Fly   446 LGAPSSQARLEIVRCLIKSVEHQLSDEEVEHVASITHGYVGADLANLVYAAMLQAQPNPLQMP-- 508

  Fly   405 VGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLI 469
                ..|.|.|...|.|:|
  Fly   509 ----HLQAALTRIKPSAMR---------------------------------------------- 523

  Fly   470 LDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELF--TGLRAPAKGLLLFGPPGNGKTLL 532
              |::.....|:|:||.||...:.|:|:.:..|.:..:.|  .|:: |.:|:|:|||||..||::
  Fly   524 --EVLIECPNVQWSDIGGQSELRLAMQQAIEWPLLHADKFQRLGIK-PPRGILMFGPPGCSKTMI 585

  Fly   533 ARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSER-----S 592
            |:|:|||....||:|....|.|.:||:.|:.||.:|..||.:.|:|:|.||:|::..||     |
  Fly   586 AKALATESKLNFLSIKGPELFSMWVGESERAVREVFRKARQVAPAIVFFDEIDAIGGERSEGDGS 650

  Fly   593 SSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPD-EQ 654
            ||......|:.|:.|.|.||:...   ..:.::||||||..:|:|.||  |..:.:||.||. |.
  Fly   651 SSGSSVKERVLTQLLTELDGVEAL---QNVTIVAATNRPDMIDKALLRPGRIDRILYVGLPQCEA 712

  Fly   655 TRELLLNRLLQKQGSPLDTEA-LRRLAKITDGYSGSDLTALAKDAALEPIRE-LNVEQVKCLDIS 717
            .||:|..:|   :..|:..:. :.:|.::|:||||:::.|:..:|||..:.: ...|.||.
  Fly   713 RREILKIKL---RAMPISNDVDMEKLVQLTEGYSGAEIQAVCHEAALRALEQSFEAEDVKW---- 770

  Fly   718 AMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDY 753
                   .||..:||.:....:|:.|..||    ||
  Fly   771 -------TDFEHALKAVPPRTSPELLKLYE----DY 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	16/64 (25%)
		P-loop_NTPase	482..>538	CDD:304359	22/57 (39%)
		AAA	515..652	CDD:214640	59/143 (41%)
		AAA	519..650	CDD:278434	56/137 (41%)
		Vps4_C	<722..754	CDD:286426	10/32 (31%)
CG5776	NP_001260420.1	SpoVK	288..785	CDD:223540	139/540 (26%)
		AAA	307..447	CDD:278434	28/130 (22%)
		AAA	572..707	CDD:278434	56/137 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810