Protein Alignment spas and Atad1

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001030174.1
• Gene: Atad1 / 309532
• RGDID: 1308570
• Length: 361
• Species: Rattus norvegicus
• Alignment Length: 293
• Identity: 115/293 - (39%)
• Similarity: 179/293 - (61%)
• Gaps: 19/293 - (6%)

  Fly   456 VSVKGV-----EQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLR-- 513
            :.||.|     |..:...::|.:   ...|.|:||||.|.....|::.||||..:..||...|
  Rat    62 IGVKNVKLSEYEMSIAAHLVDPL---NMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLL 123

  Fly   514 APAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSI 578
            .|.||:||:||||.||||:|:|.|.|....|:|:..::||.|:.|:.:||..|:|::|..:||||
  Rat   124 QPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSI 188

  Fly   579 IFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGD---RIVVLAATNRPQELDEAALR 640
            |||||:||.|..||||:|||:..:|.:|:..:|||    |.|   :::|:.||||||:||.|.:|
  Rat   189 IFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGL----DTDHSCQVIVMGATNRPQDLDSAIMR 249

  Fly   641 RFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRE 705
            |...|.:::.|..:.||.:|..:|:.:......:.| .:|:.|||:|||||..:.:||||..:||
  Rat   250 RMPTRFHINQPALKQREAILKLILKNENVDRHVDLL-EVAQETDGFSGSDLKEMCRDAALLCVRE 313

  Fly   706 -LNVEQVKCLDISAMRAITEQDFHSSLKRIRRS 737
             :|....:..|...:|.:.:||.|.:::::::|
  Rat   314 YVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKS 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		RecA-like_spastin	484..648	CDD:410932	80/168 (48%)
		AAA_lid_3	676..727	CDD:465537	20/51 (39%)
		Vps4_C	<722..754	CDD:462762	4/16 (25%)
Atad1	NP_001030174.1	SpoVK	4..344	CDD:440232	114/289 (39%)
		RecA-like_ATAD1	92..257	CDD:410928	80/168 (48%)