Protein Alignment spas and Trip13

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001011930.1
• Gene: Trip13 / 292206
• RGDID: 1308516
• Length: 432
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 69/317 - (21%)
• Similarity: 119/317 - (37%)
• Gaps: 90/317 - (28%)

  Fly   441 INNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEG----------GAKVE--WTDIAGQDVAKQ 493
            :|..|||...                   |||..|.          .|:..  |..:......|.
  Rat   102 LNEEGPSSEN-------------------LDEETENIIAASHWVLPAAEFHGLWDSLVYDVEVKS 147

  Fly   494 ALQEMVIL------PSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECS---------AT 543
            .|.:.|:.      .:|...|.|..|.    :||.||||.|||.|.:|:|.:.:         ..
  Rat   148 HLLDYVMTTLLFSDKNVDSNLITWNRV----VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQ 208

  Fly   544 FLNISAASLTSKYVGDGEKLVRALFAVARHM---QPSIIF--IDEVDSLLSERSS----SEHEAS 599
            .:.|::.||.||:..:..|||..:|...:.:   :.:::|  ||||:||.:.|::    :|...:
  Rat   209 LIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKEALVFVLIDEVESLTAARNACRAGAEPSDA 273

  Fly   600 RRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQT--------- 655
            .|:....|.:.|.:..:   ..:|:|..:|..:::|.|.:.|...:.|:..|....
  Rat   274 IRVVNAVLTQIDQIKRH---SNVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCL 335

  Fly   656 ------------------RELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTAL 694
                              |||.:...::...|.|.. .|..:::.::|.||..|..|
  Rat   336 EELMKCQIIYPRQQLLTLRELEMIGFIENNVSKLSL-LLSEISRKSEGLSGRVLRKL 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		RecA-like_spastin	484..648	CDD:410932	46/187 (25%)
		AAA_lid_3	676..727	CDD:465537	6/19 (32%)
		Vps4_C	<722..754	CDD:462762
Trip13	NP_001011930.1	McrB	34..>205	CDD:441011	29/125 (23%)
		RecA-like_Pch2-like	121..319	CDD:410916	48/204 (24%)