Sequence 1: | NP_651206.3 | Gene: | spas / 42846 | FlyBaseID: | FBgn0039141 | Length: | 758 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_037377.1 | Gene: | VPS4A / 27183 | HGNCID: | 13488 | Length: | 437 | Species: | Homo sapiens |
Alignment Length: | 368 | Identity: | 132/368 - (35%) |
---|---|---|---|
Similarity: | 196/368 - (53%) | Gaps: | 60/368 - (16%) |
- Green bases have known domain annotations that are detailed below.
Fly 435 QRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMV 499
Fly 500 ILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATEC-SATFLNISAASLTSKYVGDGEKL 563
Fly 564 VRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAAT 628
Fly 629 NRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTA 693
Fly 694 LAKDAALEPIRELN-----------------------------------------------VEQV 711
Fly 712 KCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQDYG 754 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
spas | NP_651206.3 | MIT_spastin | 230..308 | CDD:239142 | |
P-loop_NTPase | 482..>538 | CDD:304359 | 34/55 (62%) | ||
AAA | 515..652 | CDD:214640 | 77/137 (56%) | ||
AAA | 519..650 | CDD:278434 | 74/131 (56%) | ||
Vps4_C | <722..754 | CDD:286426 | 9/31 (29%) | ||
VPS4A | NP_037377.1 | Interaction with CHMP1B | 1..84 | 0/4 (0%) | |
PTZ00454 | 4..348 | CDD:240423 | 118/270 (44%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 75..106 | 4/26 (15%) | |||
RecA-like_VPS4 | 121..291 | CDD:410929 | 94/171 (55%) | ||
Vps4_C | 374..434 | CDD:401324 | 12/69 (17%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |