Sequence 1: | NP_651206.3 | Gene: | spas / 42846 | FlyBaseID: | FBgn0039141 | Length: | 758 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_033529.3 | Gene: | Vcp / 269523 | MGIID: | 99919 | Length: | 806 | Species: | Mus musculus |
Alignment Length: | 648 | Identity: | 167/648 - (25%) |
---|---|---|---|
Similarity: | 280/648 - (43%) | Gaps: | 145/648 - (22%) |
- Green bases have known domain annotations that are detailed below.
Fly 170 KEQQQSLNHPSELNREG-DGQEQQLS----------NQPQRFRPIQPLEMAANRPGGGY----SP 219
Fly 220 GPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELE------------DGI 272
Fly 273 AVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKT 337
Fly 338 REPMLAGMTNEPMKL--RVRSSGYGPKATTSAQPTASGRK--LTIGSKRPVNLA-------VANK 391
Fly 392 SQTLPRNLG-------SKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGS 449
Fly 450 GASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFT--GL 512
Fly 513 RAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPS 577
Fly 578 IIFIDEVDSLLSERSSSEHE---ASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAAL 639
Fly 640 R--RFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAALEP 702
Fly 703 IR-----ELNVEQVKCLDISAMRAITEQD---------FHSSLKRIRRSVAPQSLNSYEKWSQ 751 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
spas | NP_651206.3 | MIT_spastin | 230..308 | CDD:239142 | 13/89 (15%) |
P-loop_NTPase | 482..>538 | CDD:304359 | 28/57 (49%) | ||
AAA | 515..652 | CDD:214640 | 54/141 (38%) | ||
AAA | 519..650 | CDD:278434 | 50/135 (37%) | ||
Vps4_C | <722..754 | CDD:286426 | 10/39 (26%) | ||
Vcp | NP_033529.3 | CDC48 | 25..764 | CDD:273521 | 167/648 (26%) |
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 708..727 | 5/19 (26%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 768..806 | ||||
Interaction with UBXN6. /evidence=ECO:0000250 | 797..806 | ||||
PIM motif. /evidence=ECO:0000250|UniProtKB:P55072 | 802..806 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG0464 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |