Protein Alignment spas and ZK938.3

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001364588.1
• Gene: ZK938.3 / 191468
• WormBaseID: WBGene00014160
• Length: 616
• Species: Caenorhabditis elegans
• Alignment Length: 492
• Identity: 100/492 - (20%)
• Similarity: 168/492 - (34%)
• Gaps: 155/492 - (31%)

  Fly   226 LAKQKHH------------HRRAFEYISKALKIDEEN-EGHKE---LAIELYRKGIKELEDGI-A 273
            :...:||            .|.:|........||.|| |..:|   |:||.....|::||... |
 Worm   162 IGHHEHHLEVKRACQEQKAFRESFLKTQTDFDIDFENAEAEQETQLLSIEYAVLIIQKLERKYQA 226

  Fly   274 VDCWSGRGDVWDRAQRLH------DKMQTNLSM-ARDRLHFL-----ALREQDLQMQRLSLKEKQ 326
            :...:....|.:||..||      |..|..:.: ||.|.:|.     .:||::|.:..::.:...
 Worm   227 ISRRNYVRFVRERAAELHGLKVEIDATQAAIRIQARTRGYFARKLVREMREKELNILNMTPESYI 291

  Fly   327 KEEAQSKPQKTREPMLAGMTN---------------EPMKLRVRSSGYGPKATTSAQPTASGRKL 376
            ::....:.:|.:|.:..|:..               |.:||......:.....|..:|:|
 Worm   292 RKRCAERERKRKEGLAGGVGGGEIIEQIEEFNTDLAEALKLLKTHFFFPTSDLTDIKPSA----- 351

  Fly   377 TIGSKRPVNLAVANKSQTLPRN--------------LGSKTSVGAVQRQPAKTAATPPAVRRQFS 427
                 .|::|   |..:|:.|:              |...||    ||:..|..      .|||.
 Worm   352 -----LPIDL---NNQETIFRDACFRGIVSPLAQIELSELTS----QREICKIE------NRQFK 398

  Fly   428 -SGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVA 491
             ..|:...|...||.:                .|..||  |...|:      |::|
 Worm   399 FDFRSFLVQTVCTPCS----------------LGTWQK--QKSKDQ------KMQW--------- 430

  Fly   492 KQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKY 556
                                       |||.|.|.:|||..|||::..|..|.::||     ...
 Worm   431 ---------------------------LLLSGAPDSGKTTWARAISRACHVTHVHIS-----KNV 463

  Fly   557 VGDGE-KLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGD 620
            |..|: |:...:..:|:..:..::.||.:|.:..:.....:...:.|...||.:...:      .
 Worm   464 VNMGKRKIYTVVKKLAKQEKRLLVSIDRIDVMKKDPKHKGYTHRQILLRNFLSDLSNI------K 522

  Fly   621 RIVVLAATNRP-QELDEAALRRFTKRVYVSLPDEQTR 656
            .::|:..|..| .:||......|..:..:|.|...||
 Worm   523 FVMVIGMTRVPLDDLDSYISDLFPLQATLSNPTNATR 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	27/101 (27%)
		P-loop_NTPase	482..>538	CDD:304359	12/55 (22%)
		AAA	515..652	CDD:214640	32/138 (23%)
		AAA	519..650	CDD:278434	31/132 (23%)
		Vps4_C	<722..754	CDD:286426
ZK938.3	NP_001364588.1	P-loop_NTPase	431..545	CDD:422963	30/124 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0464
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900