Protein Alignment spas and rpt-1

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_506005.1
• Gene: rpt-1 / 179641
• WormBaseID: WBGene00004501
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 579
• Identity: 139/579 - (24%)
• Similarity: 229/579 - (39%)
• Gaps: 177/579 - (30%)

  Fly   184 REGDGQEQQLSNQPQRFRPIQPLEMAANRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDE 248
            ::.|.:|::     :.|:.:...::|..:   .|..||                 |..:...:|.
 Worm    13 KKDDTKEEE-----KNFQALDEGDIAVLK---RYGQGP-----------------YAEQLKTLDA 52

  Fly   249 ENEGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDK--MQTNLSMARDRLHFLALR 311
            :.|...:...||  .|:||.:.|:|...      :||.|.   ||  ||               :
 Worm    53 DIENCLKKVNEL--SGVKESDTGLAPPA------LWDIAA---DKQAMQ---------------Q 91

  Fly   312 EQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKL-RVRS-SGYGPKATTSAQPTASGR 374
            ||.||:.|.:                  .::....::|..| .|:. :.:......|..||....
 Worm    92 EQPLQVARCT------------------KIITSDKHDPRYLINVKQFAKFVVDLADSVAPTDIEE 138

  Fly   375 KLTIGSKRPVNLAVANKSQT-LPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSR 438
            .:.:|..|       ||.|. ||              .|||.
 Worm   139 GMRVGVDR-------NKYQIHLP--------------LPAKI----------------------- 159

  Fly   439 TPINNNGPSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPS 503
                          .|.|::..||:|             ..|.::|:.|.....:.|:|:|..|.
 Worm   160 --------------DPTVTMMQVEEK-------------PDVTYSDVGGCKDQIEKLREVVETPL 197

  Fly   504 VRPELFTGLR-APAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRAL 567
            :.||.:..|. .|.||:||:||||.||||.|||||....|.|:.:..:.|..||||:|.::||.|
 Worm   198 LHPERYVNLGIEPPKGVLLYGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVREL 262

  Fly   568 FAVARHMQPSIIFIDEVDSL----LSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAAT 628
            |.:||..:..:||.||:|::    ..:....::|..|.: .|.:.:.||.  :|.|: |.||.||
 Worm   263 FEMARTKKACLIFFDEIDAVGGARFDDGQGGDNEVQRTM-LELINQLDGF--DPRGN-IKVLMAT 323

  Fly   629 NRPQELDEAALR--RFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDL 691
            |||..||.|.:|  |..::|..:|||...|..:| ::..||.|.........||::....:|:::
 Worm   324 NRPDTLDPALMRPGRLDRKVEFALPDLAGRAHIL-KIHAKQMSVERDIRYDLLARLCPNSTGAEI 387

  Fly   692 TALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWS 750
            .::..:|.:..||            :..:..||:||..::.::        :..|.|:|
 Worm   388 RSVCTEAGMFAIR------------ARRKVATEKDFLEAINKV--------VKGYAKFS 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	17/79 (22%)
		P-loop_NTPase	482..>538	CDD:304359	26/56 (46%)
		AAA	515..652	CDD:214640	59/142 (42%)
		AAA	519..650	CDD:278434	55/136 (40%)
		Vps4_C	<722..754	CDD:286426	7/29 (24%)
rpt-1	NP_506005.1	RPT1	29..432	CDD:224143	136/558 (24%)
		AAA	214..345	CDD:278434	55/134 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910