Protein Alignment spas and mspn-1

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_501860.1
• Gene: mspn-1 / 177896
• WormBaseID: WBGene00010557
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 303
• Identity: 108/303 - (35%)
• Similarity: 173/303 - (57%)
• Gaps: 34/303 - (11%)

  Fly   457 SVKGVEQKLVQLILDEIVE-------------GGAKV--EWTDIAGQDVAKQALQEMVILPSVRP 506
            |.|.|.|...:|.:|..:|             ||..|  :|.:|.|.:.....|::.:||| :|.
 Worm    42 SKKKVAQLFHELGIDRQIELSEHEIRIATQFVGGEDVGADWDEIGGCEELVAELKDRIILP-LRF 105

  Fly   507 ELFTG--LRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFA 569
            ...:|  |.:|.:|:||:||||.||||||:|||......|:|:..::||.|:.|:.:||..|:|:
 Worm   106 ASQSGSHLLSPPRGILLYGPPGCGKTLLAKAVARAAGCRFINLQVSNLTDKWYGESQKLAAAVFS 170

  Fly   570 VARHMQPSIIFIDEVDSLLSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQEL 634
            ||:..||:||||||:||.|.:|.|.:||::..:|.:|:..:||.  :..||:|:|:.|||||:::
 Worm   171 VAQKFQPTIIFIDEIDSFLRDRQSHDHESTAMMKAQFMTLWDGF--SSSGDQIIVMGATNRPRDV 233

  Fly   635 DEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITDGYSGSDLTALAKDAA 699
            |.|.|||.|.|..|.:|:.:.|..:||.:|:.: ...:|..|..:|:..:|.|||||..:.:.|.
 Worm   234 DAAILRRMTARFQVPVPNAKQRSQILNVILRNE-KINNTVNLGEIAQAAEGLSGSDLKEVCRLAL 297

  Fly   700 LEPIREL-----NVEQVKCLDISAMRAITEQDFHSSLKRIRRS 737
            |...:..     :|.|:..|:        :.||.|::.:..|:
 Worm   298 LARAKATVASGGSVNQLLPLE--------QSDFESAVHKYMRA 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		RecA-like_spastin	484..648	CDD:410932	73/165 (44%)
		AAA_lid_3	676..727	CDD:465537	13/55 (24%)
		Vps4_C	<722..754	CDD:462762	4/16 (25%)
mspn-1	NP_501860.1	RecA-like_ATAD1	84..247	CDD:410928	73/165 (44%)
		AAA_lid_3	272..>302	CDD:465537	10/29 (34%)