Protein Alignment spas and pch-2

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_495711.1
• Gene: pch-2 / 174313
• WormBaseID: WBGene00008641
• Length: 424
• Species: Caenorhabditis elegans
• Alignment Length: 219
• Identity: 58/219 - (26%)
• Similarity: 90/219 - (41%)
• Gaps: 46/219 - (21%)

  Fly   519 LLLFGPPGNGKTLLARAVATECS---------ATFLNISAASLTSKYVGDGEKLVRALFAVARHM 574
            :||.||||.|||.|.:.:|...|         :..|.|::.||.||:..:..|||:.:|.....:
 Worm   175 ILLTGPPGTGKTSLCKGLAQHLSIRMNDKYSKSVMLEINSHSLFSKWFSESGKLVQKMFDQIDEL 239

  Fly   575 QPS-----IIFIDEVDSL--LSERSSSEHEASRRLK--TEFLVEFDGLPGNPDGDRIVVLAATNR 630
            ...     .:.||||:||  ..|.|||..|.|..::  ...|.:.|.:...   |.:::|..:|.
 Worm   240 AEDEKCMVFVLIDEVESLGMCRESSSSRSEPSDAIRAVNALLTQIDRIRRR---DNVLILCTSNL 301

  Fly   631 PQELDEAALRRFTKRVYVSLPDEQTRELLLNRL---LQKQGSPLD-------------------- 672
            ...||:|.:.|......|..|.:..|..:|...   |.:.|..:|
 Worm   302 ESTLDKALVDRADIVKNVGQPSDFARYSMLKSSIMELARIGVVIDNEVHTDYWPQDICDTKAPRN 366

  Fly   673 --TEALRRLAKITDGYSGSDLTAL 694
              ||.|.::|:...|.||..::.|
 Worm   367 EFTEILFKIAQEARGLSGRAISML 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		RecA-like_spastin	484..648	CDD:410932	43/146 (29%)
		AAA_lid_3	676..727	CDD:465537	6/19 (32%)
		Vps4_C	<722..754	CDD:462762
pch-2	NP_495711.1	McrB	13..>204	CDD:441011	12/28 (43%)
		RecA-like_Pch2-like	121..319	CDD:410916	43/146 (29%)