Protein Alignment spas and rpt-4

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001022113.1
• Gene: rpt-4 / 173384
• WormBaseID: WBGene00004504
• Length: 406
• Species: Caenorhabditis elegans
• Alignment Length: 495
• Identity: 127/495 - (25%)
• Similarity: 218/495 - (44%)
• Gaps: 133/495 - (26%)

  Fly   251 EGHKELAIELYRKGIKELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREQDL 315
            |..:..|:..||:.:.|..               |..|:|.|                 ||:::.
 Worm    19 EDERTKALNSYRRKLAECR---------------DIEQKLKD-----------------LRKKES 51

  Fly   316 QMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGS 380
            :|    .|:..|.|...|..::    :..:..|.:| ::....:..|||       :|.:..:|.
 Worm    52 EM----TKQFDKSENDIKSLQS----VGQIVGEVLK-QLSEEKFIVKAT-------NGPRYVVGC 100

  Fly   381 KRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNG 445
            :|.:|      .:.|.:  |::.|:.          .|...:.||..  |...|
 Worm   101 RRSIN------KEELKQ--GTRVSLD----------MTTLTIMRQLP--REVDP----------- 134

  Fly   446 PSGSGASTPVVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELF- 509
                                  |:.....|....:.::|:.|.....:.|:|:|.||.:.||||
 Worm   135 ----------------------LVYKMSHEDPGNISYSDVGGLAEQIRELREVVELPLINPELFK 177

  Fly   510 -TGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARH 573
             .|: .|.||.|||||||.||||||||||::....||.:.::::..||:|:..:::|.:|..||.
 Worm   178 RVGI-TPPKGCLLFGPPGTGKTLLARAVASQLDCNFLKVVSSAIVDKYIGESARMIREMFNYARD 241

  Fly   574 MQPSIIFIDEVDSL----LSERSSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQEL 634
            .||.|:|:||:|::    .||.:|::.|..|.| .|.|.:.||....   .::.|:.|||||..|
 Worm   242 HQPCIVFMDEIDAIGGRRFSEGTSADREIQRTL-MELLNQLDGFDSL---GKVKVIMATNRPDTL 302

  Fly   635 DEAALR--RFTKRVYVSLPDEQTRELLL---NRLLQKQGSPLDTEALRRLAKITDGYSGSDLTAL 694
            |.|.||  |..:::.:.||:||:|..:|   :..:.|.|. :|.||   :.|::||:|.:||..:
 Worm   303 DPALLRPGRLDRKIEIGLPNEQSRLEILKIHSNKITKHGE-IDFEA---VVKLSDGFSAADLRNV 363

  Fly   695 AKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKRI 734
            ..:|.:..||            :....:.::||..:::::
 Worm   364 CTEAGMFAIR------------AEREFVIDEDFMKAVRKV 391

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	9/56 (16%)
		P-loop_NTPase	482..>538	CDD:304359	31/57 (54%)
		AAA	515..652	CDD:214640	59/142 (42%)
		AAA	519..650	CDD:278434	55/136 (40%)
		Vps4_C	<722..754	CDD:286426	2/13 (15%)
rpt-4	NP_001022113.1	RPT1	21..404	CDD:224143	126/493 (26%)
		AAA	188..320	CDD:278434	55/135 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910