Protein Alignment spas and mei-1

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001370150.1
• Gene: mei-1 / 172612
• WormBaseID: WBGene00003183
• Length: 475
• Species: Caenorhabditis elegans
• Alignment Length: 504
• Identity: 167/504 - (33%)
• Similarity: 249/504 - (49%)
• Gaps: 84/504 - (16%)

  Fly   277 WSGRGDVWDRAQRLHDKMQTNLSMA-RD----RLHFLALREQDLQMQRLSLK-EKQKEEAQSK-- 333
            |:..||:  ..|.:.|.....:|.: ||    |..||...|.:|::.:.::: |....||.::
 Worm    28 WNEAGDL--LRQLMTDVKSCKISASNRDEHDARNTFLRALEANLKLVQQNVRDEDDLHEAMTRQS 90

  Fly   334 --PQKTREPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLP 396
              |:...:|.:....:.|:.   .||.:|  ||          |..:|:..|           .|
 Worm    91 GSPEPPADPDVWSKPSPPLP---SSSKFG--AT----------KKGVGAAGP-----------RP 129

  Fly   397 RNLGSKTSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGV 461
            |.:...||          :.:|.||      ..:...|.:...|.|:.|.|...::.....|:.|
 Worm   130 REISKSTS----------SMSTNPA------DVKPANPTQGILPQNSAGDSFDASAYDAYIVQAV 178

  Fly   462 EQKLV-----QLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLL 521
            ...:.     .:.||            ||.|....||.|.|.|.||.:.||.|.|||:|.|.::|
 Worm   179 RGTMATNTENTMSLD------------DIIGMHDVKQVLHEAVTLPLLVPEFFQGLRSPWKAMVL 231

  Fly   522 FGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDS 586
            .||||.||||:|||:|:|.|:||..:|:..|:||:.||.||:||.||.:||...||||||||:|:
 Worm   232 AGPPGTGKTLIARAIASESSSTFFTVSSTDLSSKWRGDSEKIVRLLFELARFYAPSIIFIDEIDT 296

  Fly   587 LLSER-SSSEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSL 650
            |..:| :|.|||||||:|:||||:.||.....|..|:.||||||.|.|||||..|||.||:::.|
 Worm   297 LGGQRGNSGEHEASRRVKSEFLVQMDGSQNKFDSRRVFVLAATNIPWELDEALRRRFEKRIFIPL 361

  Fly   651 PDEQTRELLLNRLLQKQGSPLDTEA-LRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCL 714
            ||...|:.|:.:.:  :|:|...|. ...||..|:|:||:|:.:|.:.||:..:|.......|.|
 Worm   362 PDIDARKKLIEKSM--EGTPKSDEINYDDLAARTEGFSGADVVSLCRTAAINVLRRYFRYDTKSL 424

  Fly   715 DISAMRAITEQ---------DFHSSLKRIRRSVAPQSLNSYEKWSQDYG 754
            ....:.|..|.         ||.::|:.:..|..|.::...::|...:|
 Worm   425 RGGELTAAMESLKAELVRNIDFEAALQAVSPSAGPDTMLKCKEWCDSFG 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	9/35 (26%)
		P-loop_NTPase	482..>538	CDD:304359	30/55 (55%)
		AAA	515..652	CDD:214640	79/137 (58%)
		AAA	519..650	CDD:278434	76/131 (58%)
		Vps4_C	<722..754	CDD:286426	7/40 (18%)
mei-1	NP_001370150.1	RecA-like_VPS4-like	195..359	CDD:410917	93/163 (57%)
		AAA_lid_3	383..423	CDD:407720	12/39 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910