Protein Alignment spas and LOC1280704

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_320566.4
• Gene: LOC1280704 / 1280704
• VectorBaseID: AGAMI1_011266
• Length: 860
• Species: Anopheles gambiae
• Alignment Length: 594
• Identity: 118/594 - (19%)
• Similarity: 217/594 - (36%)
• Gaps: 178/594 - (29%)

  Fly   170 KEQQQSL----NHPSE--------LNREGDGQEQQ----LSNQPQRFRPIQPLEMAANRPGGGYS 218
            ||.|:..    :.|||        |:|:|...|..    ||::..:.:
Mosquito   358 KEYQKRTGRLPDFPSEEAGGSRHLLSRQGTESEMSRSSVLSSRESKLK----------------- 405

  Fly   219 PGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIA--VDCWSGRG 281
             |.|...||::|.......|.:.||.|             .:....:.|::.||.  .:.|.|:.
Mosquito   406 -GSGKEKLAQKKPGELSLEEGLDKAFK-------------PMQSSFLPEIKSGIEEYTEVWKGKD 456

  Fly   282 DVWDRAQRLHDKM---------QTNLSMARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKT 337
            :..:..|..:|.|         :..|....|.     :..|:|::.:::|:..:..:...|..|
Mosquito   457 ESQNLRQTYYDDMIYEEKYADVEAELRRIVDE-----IMRQELELLQIALERDRGGKKLKKSSK- 515

  Fly   338 REPMLAGMTNEPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSK 402
                           :.|.||            ..|:|     |:..:|.....:::|...|
Mosquito   516 ---------------KARRSG------------KKGKK-----KKDKDLTPDRTTESLFEEL--- 545

  Fly   403 TSVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNGPSGSGASTPVVSVKGVEQKLVQ 467
            .:.|.:::.|                                       .||:.|..|......:
Mosquito   546 VTNGIIKKYP---------------------------------------ETPIKSYVGDLSYAAR 571

  Fly   468 LILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLL 532
            ..|:.             :..|| :|.:::..||| :..|.........|.||:.||.|:|||.|
Mosquito   572 SALNP-------------SPGDV-RQLIKQYCILP-LGSETIRNFGPCIKSLLIAGPKGSGKTSL 621

  Fly   533 ARAVATECSATFLNISAASLTSKYVGDGE--KLVRALFAVARHMQPSIIFIDEVDS-LLSERSSS 594
            ..|:.||..:...:||..::..||.|...  .|:..:..|:|.:|||:|:..:.:. .:.:...:
Mosquito   622 VHAICTETGSVLFDISPPNIVGKYPGKSGLIMLMHLISKVSRLLQPSVIYFGDAEKPFMKKIPKT 686

  Fly   595 EHEASRRLKTEFLVEFDGLPG-----NPDGDRIVVLAATNRPQELD-EAALRRFTKRVYVSLPDE 653
            :....:|||.:       ||.     .|: |||:::..::.|.|.| :..::.:.:.:|:..||.
Mosquito   687 DRTDPKRLKKD-------LPKLVKNIQPE-DRIMLIGTSDCPWEGDMKLMVQTYQRFIYIPRPDY 743

  Fly   654 QTRELLLNRLLQKQGS---PLDTEALRRLAKITDGYS-GSDLTALAKDAALEPIRELNVEQVKCL 714
            .........||.....   ..||.|   :|||:|||: ||.:..:.:....:.:.:|.|..:..|
Mosquito   744 GALSFAWKELLSHYSGVHRQFDTGA---MAKISDGYTIGSVVRCIREVITCKRMLQLRVHPLTHL 805

  Fly   715 D-ISAMRAI 722
            : |:|:.|:
Mosquito   806 ELINALSAL 814

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	15/88 (17%)
		RecA-like_spastin	484..648	CDD:410932	44/172 (26%)
		AAA_lid_3	676..727	CDD:465537	14/49 (29%)
		Vps4_C	<722..754	CDD:462762	0/1 (0%)
LOC1280704	XP_320566.4	None