Protein Alignment spas and LOC1278195

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_317745.2
• Gene: LOC1278195 / 1278195
• VectorBaseID: AGAMI1_012571
• Length: 626
• Species: Anopheles gambiae
• Alignment Length: 606
• Identity: 199/606 - (32%)
• Similarity: 313/606 - (51%)
• Gaps: 104/606 - (17%)

  Fly   235 RAFEYI--SKALKIDEENEGHKELAIELYRKGIKELE------DGIAVDCWSGRGDVWD-----R 286
            |...|:  :::|:||:|     .|:.:|..:|:.:.:      ||:...|    .||.:     .
Mosquito    35 RNLNYLLHTESLQIDDE-----RLSAQLLSEGLHKYQDLMTNPDGVNNYC----DDVLELLNTQP 90

  Fly   287 AQRLHDKMQTNLSMARDRLHFLALR------------EQDLQMQRLSL---KEKQKEE------- 329
            ::...|..:...:...|.:.:|...            |.:|...:|:.   |.||.||
Mosquito    91 SEMADDDFEITDTALDDPVSYLPSEDCACYGSYENCCEDELSPTKLASILHKSKQCEEQHQQRID 155

  Fly   330 --AQSKPQKTREPMLAGMTN----EPMKLRVRSSGYGPKATTSAQPTASGRKLTIGSKRPVNLAV 388
              ..::..|.:....|..|:    |.:..||.::|..|..|.....|..      .||.|..:.|
Mosquito   156 NRVDNRETKQQPAAAAAATSYTVIEDISRRVFANGGNPAFTPKLPVTKP------ASKPPPAVPV 214

  Fly   389 ANKSQTLPRNLGSKTSVGA----------VQRQPAKTAATPPAVRRQFSSGRNT----------- 432
            .:..:  |:::..:...|.          :|.........||.....|:.||.|
Mosquito   215 PDHQE--PKSVFHEGCSGGAFRTAKDELHIQNMKKYGTTNPPGKAPLFAYGRKTLGGRRMLGSKF 277

  Fly   433 -PPQRS-------RTPIN--NNGPSGS--GASTPVVS------------VKGVEQKLVQLILDEI 473
             .|.||       ..|.|  ::|.||.  |.|....|            ::.::.|:|:||..||
Mosquito   278 VCPVRSDNEDRSTGAPHNGSDDGRSGQYRGYSNDNSSNEDSQEDEIDERLRNIDPKMVELIRSEI 342

  Fly   474 VEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVAT 538
            ::....:.|.||||.:.||..::|.|:.|.:||::|||||.|.:|:|||||||.||||:.:.:|:
Mosquito   343 MDRFQPLSWDDIAGLEYAKTIIKEAVVWPILRPDIFTGLRKPPRGILLFGPPGTGKTLIGKCIAS 407

  Fly   539 ECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEASRRLK 603
            :..:||.:|||:|||||::|||||:||||||||...||:::||||:||||.:||.:|||:|||||
Mosquito   408 QSKSTFFSISASSLTSKWIGDGEKMVRALFAVAAVHQPAVVFIDEIDSLLCQRSDTEHESSRRLK 472

  Fly   604 TEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQG 668
            |||||:.|| ....:.:||:::.||||||||||||.||..||:|:.||:...|..:|||||.::.
Mosquito   473 TEFLVQLDG-AATAEDERILIVGATNRPQELDEAARRRLVKRLYIPLPERSARIQILNRLLDRER 536

  Fly   669 SPLDTEALRRLAKITDGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRAITEQDFHSSLKR 733
            :.|:|:.:.|:..:|:|:||:|:..|..:|::.|||.:..:|:..:....:|.|..:||..:|.:
Mosquito   537 NSLETDEIARIGDLTEGFSGADMKVLCHEASMGPIRSIPFDQLGDIAKDQVRPICYEDFRLALTK 601

  Fly   734 IRRSVAPQSLNSYEKWSQDYG 754
            ::.||:...|..|..|.:.||
Mosquito   602 VKASVSQDDLQQYVVWDRTYG 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	16/85 (19%)
		RecA-like_spastin	484..648	CDD:410932	98/163 (60%)
		AAA_lid_3	676..727	CDD:465537	14/50 (28%)
		Vps4_C	<722..754	CDD:462762	9/31 (29%)
LOC1278195	XP_317745.2	None