Protein Alignment spas and Pex6

DIOPT Version :10

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: XP_063122650.1
• Gene: Pex6 / 117265
• RGDID: 621637
• Length: 1034
• Species: Rattus norvegicus
• Alignment Length: 336
• Identity: 115/336 - (34%)
• Similarity: 154/336 - (45%)
• Gaps: 76/336 - (22%)

  Fly   480 VEWTDIAG-QDVAKQALQEMVILPSVRPELFT-GLRAPAKGLLLFGPPGNGKTLLARAVATECSA 542
            |.|.|:.| |||.|:.| |.:.||...|||.: |||  ..||||.||||.||||||:|||||||.
  Rat   700 VSWHDVGGLQDVKKEIL-ETIQLPLEHPELLSLGLR--RSGLLLHGPPGTGKTLLAKAVATECSL 761

  Fly   543 TFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSSEHEAS--RRLKTE 605
            |||::....|.:.|||..|:.||.:||.||...|.|||.||:|||...|..|.....  .|:.::
  Rat   762 TFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQ 826

  Fly   606 FLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALR--RFTKRVYVSLPDEQTRELLLNRLLQKQG 668
            .|.|.|||....|   :.|:.|||||..||.|.||  ||.|.|:|...:::..:|   |:|....
  Rat   827 LLAELDGLHSTQD---VFVIGATNRPDLLDPALLRPGRFDKLVFVGASEDRASQL---RVLSAIT 885

  Fly   669 SPLDTEALRRLAKITD----GYSGSDLTALAKDAAL-------------EPIRELNVEQ------ 710
            .....||...|..:.|    ..:|:||.:|..||.:             ||:..|:..|
  Rat   886 RKFKLEASVSLMNVLDCCPPQLTGADLYSLCSDAMMTALKRRVRDLEEGEPLPALDGNQETRGDS 950

  Fly   711 ----------------VKCLDI----------------------SAMRAITEQDFHSSLKRIRRS 737
                            :..|.|                      |:...:|.:|...:..|::.|
  Rat   951 PGIPEERLSRRHLPRLLSYLGIDYSWGQGSGLTVPRHPSGLEPRSSALLLTMEDLLQAAARLQPS 1015

  Fly   738 VAPQSLNSYEK 748
            |:.|.|..|::
  Rat  1016 VSEQELLRYKR 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142
		RecA-like_spastin	484..648	CDD:410932	84/169 (50%)
		AAA_lid_3	676..727	CDD:465537	16/111 (14%)
		Vps4_C	<722..754	CDD:462762	8/27 (30%)
Pex6	XP_063122650.1	None