Protein Alignment spas and katnal2

DIOPT Version :9

• Sequence 1: NP_651206.3
• Gene: spas / 42846
• FlyBaseID: FBgn0039141
• Length: 758
• Species: Drosophila melanogaster
• Sequence 2: NP_001090643.1
• Gene: katnal2 / 100036615
• XenbaseID: XB-GENE-5827282
• Length: 542
• Species: Xenopus tropicalis
• Alignment Length: 589
• Identity: 186/589 - (31%)
• Similarity: 282/589 - (47%)
• Gaps: 126/589 - (21%)

  Fly   242 KALKIDEENEGHKELAIELYRKGI------KELEDGIAVDCWSGRGDVWDRAQRLHDKMQTNLSM 300
            :||::..:|...:||..|..||.:      ..|::|           ..|.|..|  :.:|.:|:
 Frog     6 QALRVASQNREAEELRTEARRKNLLILIMHYLLQEG-----------YMDSANSL--EQETKISL 57

  Fly   301 ARDRLHFLALREQDLQMQRLSLKEKQKEEAQSKPQKTREPMLAGMTNEPMKLRVRSSGYGPKATT 365
            .|    |......||:...:..:.....:.|..|:.|::.:       ....||:|
 Frog    58 RR----FDVCDNVDLETILMEYESYYYIKFQKYPKITKKAL-------DHDSRVQS--------- 102

  Fly   366 SAQPTASGRKLTIGSKRPVNLAVANKSQTLPRNLGSKTSVGAVQRQPA-----KTAATPPAVRRQ 425
              :|.::|:....||         |.:|.||| :..:|    |..:|.     :|.|...|:.|:
 Frog   103 --KPRSAGKLRRAGS---------NSTQGLPR-IAQQT----VLHRPVSGSYFRTHAHQKALSRE 151

  Fly   426 FS---SGRNTPPQRSRTPINNNG---PSGSGAST---PVV--------SVKGVEQ---------- 463
            .|   :|.|:|.:.|...:|.:.   .||.|..|   .|:        ::||..|
 Frog   152 NSKQENGGNSPREASEIGLNVSAISKTSGEGGQTRRRQVIDFRSMIQDTIKGASQEIALNSLNCN 216

  Fly   464 ----------------------KLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRP 506
                                  :|..:|..:|......|.|.||.|.|.||:.::|.|:.|...|
 Frog   217 PDPSERLIKPVGAFIGGNSEMRELAAVISRDIYLQNPNVRWDDIIGLDAAKRLVKEAVVYPIRYP 281

  Fly   507 ELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVA 571
            :||||:.:|.|||||:||||.||||||:||||||:.||.||||:::.||:.||.|||||.||.:|
 Frog   282 QLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECNTTFFNISASTIVSKWRGDSEKLVRVLFELA 346

  Fly   572 RHMQPSIIFIDEVDSLLSERSS---SEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQE 633
            |:..||.||:||::|::|:|.:   .|||.|||:|||.||:.|||..:  .|.:.||||:|.|.|
 Frog   347 RYHAPSTIFLDELESVMSQRGTGPGGEHEGSRRMKTELLVQMDGLARS--DDLVFVLAASNLPWE 409

  Fly   634 LDEAALRRFTKRVYVSLPDEQTRELLLNRLL----QKQGSPLDTEA-LRRLAKITDGYSGSDLTA 693
            ||.|.|||..||:.|.||.::.|:.::...|    ...|..|.|:. ...|...||||||||:..
 Frog   410 LDYAMLRRLEKRILVDLPSKEARQAMIQHWLPPVSNSSGVELRTDLDYSTLGAETDGYSGSDIRL 474

  Fly   694 LAKDAALEPIREL------NVEQVKCLDISAMRAITEQDFHSSLKRIRRSVAPQSLNSYEKWSQD 752
            :.|:||:.|:|::      :..:.|.|.:.::..:|..||...|...:.| |......|..|.::
 Frog   475 VCKEAAMRPVRKIFDALENHHSEHKNLPVISLDTVTTSDFLEVLAHTKPS-AKSLAEKYAAWQKE 538

  Fly   753 YGDI 756
            :..:
 Frog   539 FESV 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spas	NP_651206.3	MIT_spastin	230..308	CDD:239142	16/71 (23%)
		P-loop_NTPase	482..>538	CDD:304359	33/55 (60%)
		AAA	515..652	CDD:214640	82/139 (59%)
		AAA	519..650	CDD:278434	78/133 (59%)
		Vps4_C	<722..754	CDD:286426	8/31 (26%)
katnal2	NP_001090643.1	LisH	25..57	CDD:128913	8/44 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..126		12/59 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..168		8/25 (32%)
		SpoVK	<245..526	CDD:223540	126/283 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910