Protein Alignment Miro and MIRO1

DIOPT Version :9

• Sequence 1: NP_001262895.1
• Gene: Miro / 42845
• FlyBaseID: FBgn0039140
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001031953.1
• Gene: MIRO1 / 832814
• AraportID: AT5G27540
• Length: 648
• Species: Arabidopsis thaliana
• Alignment Length: 638
• Identity: 219/638 - (34%)
• Similarity: 343/638 - (53%)
• Gaps: 72/638 - (11%)

  Fly     1 MGQYTA------SQRKNVRILLVGDAGVGKTSLILSLVSEEYPEEVPPRAEEITIPANVTPEQVP 59
            |.:|.|      ...|:|||::|||.|.||:|||::..::.:|..|||...:..:|....|:.:|
plant     1 MARYAAGAVDCPGSPKSVRIVVVGDKGTGKSSLIVAAATDSFPPNVPPVLPDYKLPIEFFPDGIP 65

  Fly    60 TSIVDFSAVEQSEDALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEA 124
            .:|||.|:..:..|.:|.|:.:|..|.:.||.|..:||:|::.:|||.:|
plant    66 VTIVDTSSRPEDRDIVAEELKRADAVVLTYACDRPETLERLSEYWLPELR--------------- 115

  Fly   125 EAEGDTQREPIRKPIVLVGNKIDLIEYS---TMDSVLA-IMEDYPEIESCVECSAKSLHNISEMF 185
                   |..::.||::.|.|:|..:.:   :::.|:: ||:.:.|||:|:||||.......|:|
plant   116 -------RLEVKIPIIVAGCKLDFRDDNNQVSLEQVMSPIMQQFREIETCIECSALKQLQAQEVF 173

  Fly   186 YYAQKAVLHPTSPLYMMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQ 250
            |||||.|||||.||:..:.|.|...|.::|.|||.:||.|.|..|::.|||.||.:||:.||||.
plant   174 YYAQKTVLHPTGPLFDQDSQALKPRCVRALKRIFILCDHDRDGALSEAELNDFQVKCFHAPLQPS 238

  Fly   251 ILDEVKAVIQKNVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRP 315
            .::.||.|:|:.:|:|:....:|:.||||||.|||::||.||||.|||:||||:.:.:.:|.|..
plant   239 EIEGVKRVVQEKLPEGVNERGLTVTGFLFLHALFIEKGRLETTWTVLRKFGYNNDIRLAEELLPS 303

  Fly   316 PL-KIPPGSSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFSTCPAAPWSYSTDIRKSCPI 379
            .: |..|..|.||::....||..::..:|.|.|..|.|:|.:.||||.|.:||       |..|.
plant   304 AIFKRAPDQSFELTNAAIDFLKGMYMLFDDDQDNNLRPQEIEDLFSTAPESPW-------KEAPY 361

  Fly   380 NETT-----GWVTLHGWLCRWTLMTLIDVVKTMEYLAYLGFNVHENDSQLAAIHVTRERRIDLAK 439
            .:..     |.::...:|..|:||||::..:::|.|.|:||   ..|.. .||.|||.||:|..|
plant   362 EDAAEKTALGGLSFDAFLSMWSLMTLLEPARSVENLIYIGF---PGDPS-TAIRVTRRRRLDRKK 422

  Fly   440 RQSSRSVYKCHVIGPKGSGKTGMCRGFLVEDMHKLIGKEFKTNVVN------CINSVQVYGQEKH 498
            :|..|.|::|.|.||..:||:.:...||        |:.:..|..:      .:|.|...|.:|.
plant   423 QQCERKVFQCFVFGPNNAGKSALLNCFL--------GRSYTDNQESTTDERYAVNMVDESGAKKT 479

  Fly   499 LILRDI--DVRHALDPLQPQEVNCDVACLVYDSSNPRSFEYVARIYIKY--YAES---KIPVMIV 556
            ||:|:|  |....|...:.....||:|..|||||:..|::...::.::.  |.|:   ::|.::|
plant   480 LIMREIPEDGVQGLFSSKESLAACDIAVFVYDSSDESSWKRATQLLVEVANYGEATGYEVPCLMV 544

  Fly   557 GTKCDMDERRQDYLMQPSEFCDKYKLLPPHLFSLKTNK-KELYTKLATMAAFP 608
            ..|.|:|..... :.:.:.......:.||...|.|... ..|:.|:.|.|..|
plant   545 SAKDDLDSSPIS-IQESTRMTQDMGIEPPVSISSKLGDFNNLFRKILTAAQHP 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Miro	NP_001262895.1	Miro1	10..195	CDD:206680	65/188 (35%)
		RHO	14..195	CDD:197554	62/184 (34%)
		EF_assoc_2	247..328	CDD:285547	38/81 (47%)
		EF_assoc_1	367..437	CDD:285546	23/74 (31%)
		Miro2	444..620	CDD:206679	47/179 (26%)
		Ras	448..602	CDD:278499	42/167 (25%)
MIRO1	NP_001031953.1	Miro1	16..183	CDD:206680	65/188 (35%)
		EF_assoc_2	233..320	CDD:369829	40/86 (47%)
		EF_assoc_1	356..>408	CDD:369828	16/62 (26%)
		Miro2	426..608	CDD:206679	47/180 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	120	1.000	Domainoid score	I1885
eggNOG	1	0.900	-	-		E2759_KOG1707
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	381	1.000	Inparanoid score	I532
OMA	1	1.010	-	-		QHG55756
OrthoDB	1	1.010	-	-		D538388at2759
OrthoFinder	1	1.000	-	-		FOG0001617
OrthoInspector	1	1.000	-	-		otm3306
orthoMCL	1	0.900	-	-		OOG6_101658
Panther	1	1.100	-	-	LDO	PTHR24072
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1026
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840