DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Miro and RhoL

DIOPT Version :9

Sequence 1:	NP_001262895.1	Gene:	Miro / 42845	FlyBaseID:	FBgn0039140	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_001247003.1	Gene:	RhoL / 41136	FlyBaseID:	FBgn0014380	Length:	214	Species:	Drosophila melanogaster

Alignment Length:	197	Identity:	47/197 - (23%)
Similarity:	79/197 - (40%)	Gaps:	32/197 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TASQRKN---VRILLVGDAGVGKTSLILSLVSEEYPEE-VPPRAEEITIPANVTPEQVPTSIVDF 65
            ||:..|:   ::|.:|||..||||.::::....|:||| :|...:.......|.......::.|.
  Fly    26 TANITKSPRPLKITIVGDGMVGKTCMLITYTRNEFPEEYIPTVFDNHACNIAVDDRDYNLTLWDT 90

  Fly    66 SAVEQSEDALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDT 130
            :..|..|..........:...:.|::....:.:.:.|.|.|.:|
  Fly    91 AGQEDYERLRPLSYPSTNCFLLCYSISSRTSFENVKSKWWPEIR--------------------- 134

  Fly   131 QREPIRKPIVLVGNKIDLIEYSTMDSVLAIMED---YPEIE--SCVECSAKSLHNISEMFYYAQK 190
             ......|:||||.|:|| .....:..:...|.   ..||.  :.||||||...|:.::|..|.:
  Fly   135 -HFSAHVPVVLVGTKLDL-RIPNSEKFVTTQEGKKMRKEIHAFNLVECSAKKKQNLQQVFEEAVR 197

  Fly   191 AV 192
            ||
  Fly   198 AV 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Miro	NP_001262895.1	Miro1	10..195	CDD:206680	45/192 (23%)
		RHO	14..195	CDD:197554	44/185 (24%)
		EF_assoc_2	247..328	CDD:285547
		EF_assoc_1	367..437	CDD:285546
		Miro2	444..620	CDD:206679
		Ras	448..602	CDD:278499
RhoL	NP_001247003.1	Rho	36..198	CDD:206641	42/184 (23%)
RhoL	NP_001247003.1	RHO	38..202	CDD:197554	44/185 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1464
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.050