DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Miro and Cdc42

DIOPT Version :9

Sequence 1:	NP_001262895.1	Gene:	Miro / 42845	FlyBaseID:	FBgn0039140	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster

Alignment Length:	204	Identity:	46/204 - (22%)
Similarity:	83/204 - (40%)	Gaps:	38/204 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 KNVRILLVGDAGVGKTSLILSLVSEEYPEE-VPPRAEEITIPANVTPEQVPTSIVDFSAVEQSED 73
            :.::.::|||..||||.|::|..:.::|.| ||...:...:...:..|.....:.|.:..|..:.
  Fly     2 QTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDR 66

  Fly    74 ALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDTQREPIRKP 138
            .......:..|..:.::|....:.:.:...|:|.:...|.                      :.|
  Fly    67 LRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQ----------------------KTP 109

  Fly   139 IVLVGNKIDL-IEYSTMDSVLAIMEDYP-----------EIESC--VECSAKSLHNISEMFYYAQ 189
            .:|||.:||| .|.||::. ||..:..|           |:::.  |||||.:...:..:|..|.
  Fly   110 FLLVGTQIDLRDENSTLEK-LAKNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAI 173

  Fly   190 KAVLHPTSP 198
            .|.|.|..|
  Fly   174 LAALEPPEP 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Miro	NP_001262895.1	Miro1	10..195	CDD:206680	44/199 (22%)
		RHO	14..195	CDD:197554	44/195 (23%)
		EF_assoc_2	247..328	CDD:285547
		EF_assoc_1	367..437	CDD:285546
		Miro2	444..620	CDD:206679
		Ras	448..602	CDD:278499
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	43/196 (22%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	44/195 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466326
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030