Protein Alignment Miro and Miro

DIOPT Version :10

• Sequence 1: NP_651205.2
• Gene: Miro / 42845
• FlyBaseID: FBgn0039140
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: XP_061518742.1
• Gene: Miro / 1277953
• VectorBaseID: AGAMI1_000355
• Length: 651
• Species: Anopheles gambiae
• Alignment Length: 670
• Identity: 482/670 - (71%)
• Similarity: 566/670 - (84%)
• Gaps: 23/670 - (3%)

  Fly     1 MGQYTASQRKNVRILLVGDAGVGKTSLILSLVSEEYPEEVPPRAEEITIPANVTPEQVPTSIVDF 65
            |..::.|.:::||||||||.|||||||||||||||:||:||.:||||||||:||||||||:|||:
Mosquito     1 MVAWSVSHKRHVRILLVGDQGVGKTSLILSLVSEEFPEDVPLKAEEITIPADVTPEQVPTNIVDY 65

  Fly    66 SAVEQSEDALAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDT 130
            ||.|||::|||.||.|||||||||:||.::|||.||..|||:|: ||:
Mosquito    66 SAAEQSDEALAEEIRKAHVVCIVYSVDCEETLDGITERWLPMVQ-KCS----------------- 112

  Fly   131 QREPIRKPIVLVGNKIDLIEYSTMDSVLAIMEDYPEIESCVECSAKSLHNISEMFYYAQKAVLHP 195
              |..|||:|||||||||::|||:|.||:|||||||:|||||||||:||||||||||||||||||
Mosquito   113 --EMERKPVVLVGNKIDLVDYSTIDHVLSIMEDYPEVESCVECSAKTLHNISEMFYYAQKAVLHP 175

  Fly   196 TSPLYMMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQ 260
            |:|||:||||:||.||||:||||||:||||||.||||||||.|||||||.|||||:|||||||:.
Mosquito   176 TAPLYIMEEQDLTEACKKALVRIFKVCDIDGDGLLNDYELNHFQRRCFNAPLQPQVLDEVKAVLM 240

  Fly   261 KNVPDGIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKIPPGSST 325
            ||.||||.:|:|||.||||||||||||||||||||||||||||:.|.|..|||.||:||||||||
Mosquito   241 KNTPDGIRDDSVTLSGFLFLHCLFIQRGRNETTWAVLRRFGYNESLAMSDEYLHPPVKIPPGSST 305

  Fly   326 ELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFSTCPAAPWSYSTDIRKSCPINETTGWVTLHG 390
            ||||||||||:::|||.||||||||||.|.:.|||.||:.|  :||||:::.|.|| .||.||||
Mosquito   306 ELSHRGQQFLVSLFERSDRDGDGALSPTEFQKLFSACPSPP--FSTDIKRTIPTNE-NGWPTLHG 367

  Fly   391 WLCRWTLMTLIDVVKTMEYLAYLGFNVHENDSQLAAIHVTRERRIDLAKRQSSRSVYKCHVIGPK 455
            |||||:||||:||.||:|||||||||||||:||||||||||||||||||:|:||:||.|||||.|
Mosquito   368 WLCRWSLMTLVDVNKTLEYLAYLGFNVHENESQLAAIHVTRERRIDLAKKQNSRTVYMCHVIGAK 432

  Fly   456 GSGKTGMCRGFLVEDMHKLIGKEFKTNVVNCINSVQVYGQEKHLILRDIDVRHALDPLQPQEVNC 520
            .:.||..||.||.:||.:|..::.:.:....||:||||||||:|:|||:|.|..||||||.||||
Mosquito   433 EAAKTTFCRAFLAQDMKRLTDRDIRHSNRYAINTVQVYGQEKYLVLRDVDARLVLDPLQPSEVNC 497

  Fly   521 DVACLVYDSSNPRSFEYVARIYIKYYAESKIPVMIVGTKCDMDERRQDYLMQPSEFCDKYKLLPP 585
            ||||||||..||:||||:|||||||:|||||||:|||||.|::|.||:||:||.:||.|||||.|
Mosquito   498 DVACLVYDVGNPKSFEYIARIYIKYFAESKIPVLIVGTKADLEEVRQEYLLQPPDFCHKYKLLQP 562

  Fly   586 HLFSLKTNKKELYTKLATMAAFPRFQAAWILFYKHRLVQLWESAHLRQFGLMTEDPKLWLKAGLG 650
            ..||:|.|||::||||||||||||||||||||||||||||||:.||:|||||:.||.||.|||||
Mosquito   563 QFFSVKHNKKDVYTKLATMAAFPRFQAAWILFYKHRLVQLWETTHLKQFGLMSSDPLLWWKAGLG 627

  Fly   651 VAAATMLGFIVLKTISAAGA 670
            :||||::||.|:|.....|:
Mosquito   628 IAAATIVGFFVVKAFHGPGS 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Miro	NP_651205.2	Miro1	10..195	CDD:206680	129/184 (70%)
		EF_assoc_2	245..329	CDD:462444	67/83 (81%)
		FRQ1	<333..>360	CDD:444056	18/26 (69%)
		EF_assoc_1	367..437	CDD:462443	53/69 (77%)
		Miro2	444..620	CDD:206679	120/175 (69%)
Miro	XP_061518742.1	None