Protein Alignment Mettl3 and Mettl14

DIOPT Version :9

• Sequence 1: NP_651204.1
• Gene: Mettl3 / 42844
• FlyBaseID: FBgn0039139
• Length: 608
• Species: Drosophila melanogaster
• Sequence 2: XP_006233328.1
• Gene: Mettl14 / 295428
• RGDID: 1304822
• Length: 456
• Species: Rattus norvegicus
• Alignment Length: 391
• Identity: 103/391 - (26%)
• Similarity: 152/391 - (38%)
• Gaps: 103/391 - (26%)

  Fly   238 LKAQQATAEMA------AKKKQERRDEKELRPDVDAGENVTGKVPKTESAAEDGEIIAEVINNC- 295
            |.|||..||.|      ...|.|:|:..|.|....|..:.:....| ....::||...:.:...
  Rat    18 LLAQQLGAESADSIGAVLNSKDEQREIAETRETCRASYDTSAPNSK-RKCLDEGETDEDKVEEYK 81

  Fly   296 -EAESQESTDGSDTCSSETTDKCTKLHFKKIIQAHTDESLGDCSFLNTCFHMATCKYVHYEVDTL 359
             |.|.|:..:..........|..|.|...:.:..|.|                   |..:.|||
  Rat    82 DELEMQQEEENLPYEEEIYKDSSTFLKGTQSLNPHND-------------------YCQHFVDT- 126

  Fly   360 PHINTNKPTDV------------------KTKLSLKRSVDSSCTLYPPQWIQCDLRFLDMTVL-G 405
            .|...|...||                  |.:|..|.:.       ||.::|.|:...|:..| .
  Rat   127 GHRPQNFIRDVGLADRFEEYPKLRELIRLKDELIAKSNT-------PPMYLQADIEAFDIRELTP 184

  Fly   406 KFAVVMADPP------------------WDIHMELPYGTMSDDEMRALGVPALQDDGLIFLWV-T 451
            ||.|::.:||                  ||..|:|        |:..:..|.    ..||||. :
  Rat   185 KFDVILLEPPLEEYYRETGIAANEKCWTWDDIMKL--------EIDEIAAPR----SFIFLWCGS 237

  Fly   452 GRAMELGRDCLKLWGYERVDELIWVKTNQLQRIIRTGRTGHW-----LNHGKEHCLVGMKGNPTN 511
            |..::|||.||:.|||.|.:::.|:|||:    ...|:|...     ....|||||:|:||....
  Rat   238 GEGLDLGRVCLRKWGYRRCEDICWIKTNK----NNPGKTKTLDPKAVFQRTKEHCLMGIKGTVKR 298

  Fly   512 ------LNRGLDCDVIVAEVRATSH--KPDEIYGIIERLSPGTRKIELFGRPHNIQPNWITLGNQ 568
                  ::..:|.|:|:.|.....:  ||.||:.|||....|.|::.||||...|:|.|:|:|..
  Rat   299 STDGDFIHANVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRDSTIRPGWLTVGPT 363

  Fly   569 L 569
            |
  Rat   364 L 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mettl3	NP_651204.1	MT-A70	407..568	CDD:282866	60/192 (31%)
Mettl14	XP_006233328.1	MT-A70	186..363	CDD:368270	60/192 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4725
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D383312at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820