Protein Alignment KrT95D and pacs2

DIOPT Version :9

• Sequence 1: NP_524473.2
• Gene: KrT95D / 42843
• FlyBaseID: FBgn0020647
• Length: 1175
• Species: Drosophila melanogaster
• Sequence 2: XP_009305758.1
• Gene: pacs2 / 794778
• ZFINID: ZDB-GENE-081218-1
• Length: 889
• Species: Danio rerio
• Alignment Length: 1223
• Identity: 360/1223 - (29%)
• Similarity: 514/1223 - (42%)
• Gaps: 400/1223 - (32%)

  Fly     3 MVDKSSKLVDKFAVISGTGGSGPGGGPLNLQSGGGGGGSGGGGGVSGSGGISGTAGLSAGAGMTT 67
            |.::|.:|            |.||.|.||
Zfish     1 MAERSGRL------------SFPGSGALN------------------------------------ 17

  Fly    68 GQKPVPMKLFAAWEVDRTPPNCIPRLCSLTITRLSILTPLPGDTTSLSLAVKMQSSKRTLRSHEI 132
              :||||.|||.||:|.:.|||||||||||:.:|.::..|..:..|:.:|||:|.|||.||||||
Zfish    18 --RPVPMNLFATWEIDGSSPNCIPRLCSLTLKKLFVMKALDKELISVVIAVKIQGSKRILRSHEI 80

  Fly   133 PINGLALTSSASLQGNSPMSVAGGVGGGGVGTPGSVGTGGGLGVAVPLTETELDLHFSLQYPHFI 197
                             .:..||||                        ||:|.|.||||||||:
Zfish    81 -----------------VLPPAGGV------------------------ETDLALTFSLQYPHFL 104

  Fly   198 KRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMDAVLQKSMD--MIIELTASGKN--GRPGTV 258
            ||:||:|.|||||||:||:||||||||||.|.|.|..|:|...:  .::.|.::.|.  |:
Zfish   105 KREGNKLQILLQRRKRYKNRTILGYKTLAAGSIDMAEVMQHPAEGGQVLALCSNQKEFLGK---- 165

  Fly   259 VACLRAERVSSIPVDHDNKNNNSVLLADRVA---EYSDEDEEAEFSSGEFNDEANELGLIRGYDP 320
            ||.:....:||.|:||:    .:.:|..::.   .||:|:.|:..|..|.:|:|     .:|.|.
Zfish   166 VAEIWIYSLSSQPIDHE----EAAILGQKIKCSDNYSEEEYESFSSEQEASDDA-----AQGQDL 221

  Fly   321 KDPRDYNHPAKHDMRKYRNKLQRSGIEDCALVGHHPGSIQHHHPGVVVDSDSEFEMKDKSSSRAK 385
            :                                                 |.|:|::.....|..
Zfish   222 E-------------------------------------------------DDEYEIRKPKKQRRS 237

  Fly   386 FSRTISL-QQRNFKQKIVALLKRFKVSEELEGESGHRGTAALRGERDLDALFQELESLSCCEGDD 449
            ..||.|: :|:||||::|||||||:||:|:..............|.|||     ||||......|
Zfish   238 IVRTASITRQQNFKQRVVALLKRFRVSDEVLDSEQDPAEPPPEVEEDLD-----LESLDFENPSD 297

  Fly   450 SGPDM-DSISVGSTPKPSLRPFFTNSRIMLHDNITGNGGDLSQLVGGGLGPGTGTAGNSERRSSD 513
            ||||: |..||.|||||.|:|:|.
Zfish   298 SGPDLDDDESVHSTPKPKLKPYFE----------------------------------------- 321

  Fly   514 KSDQLTNSSYNLENNKNQKCIHLTNNNNSATTPDRGGNDSSGNEGNAGYTDGQNSDPQNSPPRDK 578
                                                |...|.::...|......|..:...|.|.
Zfish   322 ------------------------------------GVSLSSSQTEIGSIHSVRSHREPPSPMDP 350

  Fly   579 DYLRLQ----QMQQQQLTPVSSVAASMGSGSVITPA---------------------QTEKRSRL 618
            |.:|..    ||..:      |...|||...|:||.                     .|:..|.:
Zfish   351 DKVRAAGGKFQMDNE------SDRVSMGHPEVVTPTTELEMMDSMDFFMERLPPIGRMTKTESLI 409

  Fly   619 FRTSSNTPANAGSGGNSVSAISASGG---GKRKHTL--SLSAEPRSVLEACLSPTNVEPRKLLLD 678
            ..::...|..||..|.|.|.......   .:|.::|  ..|.:.|..|:.        |||.:.|
Zfish   410 IPSNRVEPKLAGRRGRSTSLKERQPSRPPNERANSLDNERSLDTRCHLQI--------PRKTVYD 466

  Fly   679 QLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANSFKPAFVPQNTAEVKAVLQALMAK 743
            ||:.:.. .||.:|:.:.:|:..:..|     ..:..:..|...|......||:::|....::::
Zfish   467 QLNHILV-SDSHLPDSIILINTSDWQG-----QYVSEVLQNHGLPVVCTCTTADIQAAFSTIISR 525

  Fly   744 IQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPPDWLNHLRFYLVPVGGSCGSVARH 808
            ||::||||:..|..|:|.:.|........||.:|:.:..:.||||.:|||.::|:|  ...||::
Zfish   526 IQRFCNSNSVTPSPVRVGVAGAQHFLSVVLRLFVDHLTHKTPDWLGYLRFLIIPLG--VHPVAKY 588

  Fly   809 LSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATALTTNLADAAGVAKSDIAELVQRIQ 873
            |:.:|..|..:|....|..|..:..|..:||                       .|..::|.||.
Zfish   589 LASIDYRYNSLFLDSAWRDLFHKPEAPTSAV-----------------------QDSPDVVSRIT 630

  Fly   874 RYLLAAGPCTQIPIAEAMVNYK---------------DEDSCQIFVPFVSDVRIGYLDAQASLDL 923
            :|:|.|....|:||||||:.||               ||||||.|:||:..|::|.::
Zfish   631 QYMLGANGAHQLPIAEAMLTYKQKRKKSFHFDFAVSPDEDSCQKFIPFIGMVKVGIVE------- 688

  Fly   924 EENAAGSNAVGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISPPLQ----TPPSS 984
                  ..:|.||     .|..|.|:||       .::|.:||.|     |||.|:    |||||
Zfish   689 ------QTSVASG-----DSDDAAPVGS-------ALMSSTPPAQ-----ISPLLKEASPTPPSS 730

  Fly   985 ASSHRERNTSESLSTPSSVQQQSFSGALAAAEAVELQVDYWPLVRPGEGHAKESKGGLSKGSDAG 1049
            .|.|..       |:|...|          .|.:.||||||  :.|.|...:..|      .|:.
Zfish   731 PSVHMS-------SSPGGGQ----------GELMGLQVDYW--IAPSERKKEVEK------RDSS 770

  Fly  1050 GKNSIKSTFRNLQVWRLPQ-HAQQLGDMFNGLTVSFATKEKKQKQIMRLGKK-KDKERDLEKEQC 1112
            |||:::.|||:|||.|||| .|.........:||  .||| |.|::|.|.|| ||||.: .|.|.
Zfish   771 GKNTLRCTFRSLQVSRLPQGGADTTHQPIMSMTV--VTKE-KNKKVMFLPKKTKDKEAE-SKSQV 831

  Fly  1113 VEGVARLICSPKQSHPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFPIALIG 1165
            :||::||||:.|....: |:|.|||.||..|||||:::||.:|||:||:|:.|
Zfish   832 IEGISRLICTAKHQQTM-LKVLIDGVEWNDVKFFQLAAQWSSHVKHFPLAIFG 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KrT95D	NP_524473.2	Pacs-1	676..1167	CDD:287256	169/511 (33%)
pacs2	XP_009305758.1	Pacs-1	464..885	CDD:287256	169/511 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580649
Domainoid	1	1.000	230	1.000	Domainoid score	I2384
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15016
Inparanoid	1	1.050	438	1.000	Inparanoid score	I1645
OMA	1	1.010	-	-		QHG45439
OrthoDB	1	1.010	-	-		D151297at33208
OrthoFinder	1	1.000	-	-		FOG0002262
OrthoInspector	1	1.000	-	-		otm24714
orthoMCL	1	0.900	-	-		OOG6_102151
Panther	1	1.100	-	-	O	PTHR13280
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4164
SonicParanoid	1	1.000	-	-		X1495
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.900