Protein Alignment KrT95D and KrT95D

DIOPT Version :10

• Sequence 1: NP_524473.2
• Gene: KrT95D / 42843
• FlyBaseID: FBgn0020647
• Length: 1175
• Species: Drosophila melanogaster
• Sequence 2: XP_061496549.1
• Gene: KrT95D / 4577162
• VectorBaseID: AGAMI1_004925
• Length: 1038
• Species: Anopheles gambiae
• Alignment Length: 1153
• Identity: 637/1153 - (55%)
• Similarity: 761/1153 - (66%)
• Gaps: 179/1153 - (15%)

  Fly    70 KPVPMKLFAAWEVDRTPPNCIPRLCSLTITRLSILTPLPGDTTSLSLAVKMQSSKRTLRSHEIPI 134
            |||||||||||||||||.|||||||||.|||||:|||||.|.|||||||:||||||||||||||:
Mosquito    15 KPVPMKLFAAWEVDRTPSNCIPRLCSLKITRLSLLTPLPADLTSLSLAVRMQSSKRTLRSHEIPV 79

  Fly   135 --------NGLALTSSASLQGNSPMSVAGGV-------GGGGVGTPGSVGTGGGLGVA-----VP 179
                    ....:..:.|:.|.   :|.||:       ||||||  |.||.|||.|.|     .|
Mosquito    80 PQSLSAGYGSTGVIGTGSITGG---AVGGGLTGGTGLAGGGGVG--GGVGVGGGGGGAGQLNSPP 139

  Fly   180 LTETELDLHFSLQYPHFIKRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMDAVLQKSMDMII 244
            |.|||||||||||||||||||||||:||||||||||:||||||||||||:|||||||||||||.:
Mosquito   140 LLETELDLHFSLQYPHFIKRDGNRLLILLQRRKKYKTRTILGYKTLAEGVIRMDAVLQKSMDMTV 204

  Fly   245 ELTASGKNGRPGTVVACLRAERVSSIPVDHDNKNNNSVLLADRVAEYSDEDEEAEFSSGEFNDEA 309
            ||..|||.||.|..:|.|||.:|:|||||.|||||||:|:.|||.||||||||.|||||:.|||.
Mosquito   205 ELNGSGKAGRAGLTIATLRATQVTSIPVDQDNKNNNSLLVTDRVNEYSDEDEEQEFSSGDENDEG 269

  Fly   310 NELGLIRGYDPKDPRDYNHPAKHD-MRKYRNKLQRSGIEDCALVGHHPGSIQHHHPGVVVDSDSE 373
                 :.||..|    .|:..|.| .:|:.:..|....||..::           |....||||:
Mosquito   270 -----LSGYAAK----RNYAGKRDSYKKFESGEQDGEQEDGNML-----------PSNQADSDSD 314

  Fly   374 FEMKDKSSSRAKFSRTISLQQRNFKQKIVALLKRFKVSEELEGESGHRGTAALRGERDLDALFQE 438
            |:...|..||.|.||     ||||||:|::|||||||.|||||:...|| .||||:|||||||||
Mosquito   315 FDNMGKEKSRGKMSR-----QRNFKQRIISLLKRFKVPEELEGDVRERG-PALRGKRDLDALFQE 373

  Fly   439 LESLSCCEGDDSGPDMDSISVGSTPKPSLRPFFTNS----RIMLHDNITGNGGDLS--QLVGGGL 497
            ||||||.||||||.||||:|:||||||||||||.:|    ....|.:|     .||  |..|||:
Mosquito   374 LESLSCGEGDDSGQDMDSLSIGSTPKPSLRPFFEHSGKPVLTQQHSSI-----QLSSMQKGGGGV 433

  Fly   498 GPGTGTAG-------NSERRSS---DKSDQLTNSSYNLENNKNQKCIHLTNNNNSATTPDRGG-- 550
            |.|.|...       |.|:|.|   .||:.:|.:: ||.|:.|...|:....:|.:.:.||.|
Mosquito   434 GGGVGNKDFMPEKKPNLEKRDSLAEKKSNSITIAN-NLINSMNGNSINNNQTSNYSNSQDRSGDW 497

  Fly   551 -NDSSGNEGNAGYTDGQ--NSDPQN--SPPRDKDYLRLQQMQQQQLTPVSSVAASMGSGSVITPA 610
             ||||||||.||.||.:  :|||||  |||::|:                              .
Mosquito   498 KNDSSGNEGGAGNTDPEALSSDPQNTGSPPKEKE------------------------------T 532

  Fly   611 QTEKRSRLFRTSSNTPANAGSGGNSVSAISASGG---GKRKHTLSLSAEPRSVLEACLSPTNVEP 672
            ..||::|||||||:||.:|......:|......|   |::.|.......|   ||.|||||||||
Mosquito   533 AVEKKNRLFRTSSSTPNSAKKQKQVLSFQMDQHGQQQGQQHHNQQGKPSP---LETCLSPTNVEP 594

  Fly   673 RKLLLDQLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANSFKPAFVPQNTAEVKAVL 737
            ||.||:||.|.|..|:||:||||||:||||| ...:|..:|.:|.:.:|:|.|.|.|||||||:.
Mosquito   595 RKSLLEQLQRTFTTEESALPEVVTIVSPPEA-STMSLTPRLASLISATFRPTFQPNNTAEVKAIT 658

  Fly   738 QALMAKIQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPPDWLNHLRFYLVPVGGSC 802
            ||||.||||||||.||||.||||:|:||||||||.|||||||:|:|||||:||:|||:||: |||
Mosquito   659 QALMNKIQKYCNSTAKPPTTVKVVLVGGDWLQGAVLRHYVELLGIRPPDWVNHIRFYIVPL-GSC 722

  Fly   803 GSVARHLSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATALTTNLADAAGVAKSDIAE 867
             :|||::..:|.:|..|||:::|.|:|:|||                   ||..|.  :|::.||
Mosquito   723 -AVARYIGMIDSSYLGMFGTESWQQICDRAA-------------------NLESAQ--SKNESAE 765

  Fly   868 LVQRIQRYLLAAGPCTQIPIAEAMVNYKDEDSCQIFVPFVSDVRIGYLDA-QASLDLEENAAGSN 931
            .:.||||||::.|||||:|||||||||:||||||||||||||||||.|:. |.||||:|:...::
Mosquito   766 FINRIQRYLISGGPCTQVPIAEAMVNYRDEDSCQIFVPFVSDVRIGCLEGPQVSLDLDESFTYAS 830

  Fly   932 AVGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISPPLQTPPSSASSHRERNTSES 996
                   .|||..               ::|.||||.   ||.|||....|.:.:..::::..:.
Mosquito   831 -------QGSADR---------------MLSSSPPQS---GRTSPPASQTPGAIAQLQQKDLQQQ 870

  Fly   997 LSTPSSVQQQSFSGALAAAEAVELQVDYWPLVRPGEGHAKESKGGLSKGSDAGGKNSIKSTFRNL 1061
            |      ||.|.|.:....|::|||||||||.|| ....||..  |.||.|..||||||||||:|
Mosquito   871 L------QQSSSSSSSQVQESLELQVDYWPLARP-NFDPKEKL--LGKGQDPSGKNSIKSTFRHL 926

  Fly  1062 QVWRLPQHAQQLGDMFNGLTVSFATKEKKQKQIMRLGKKKDKERDLEKEQCVEGVARLICSPKQS 1126
            ||||||| |...|:..||||:|||||||||| ||||||||:|:||.|||||||||||||||||||
Mosquito   927 QVWRLPQ-APSFGEFTNGLTLSFATKEKKQK-IMRLGKKKEKDRDAEKEQCVEGVARLICSPKQS 989

  Fly  1127 HPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFPIALIGCTPMSCAEL 1174
            |||||||||||||||||||||:|||||||:|||||||:| .|::.||:
Mosquito   990 HPVPLRVYIDGTEWTGVKFFQLSSQWQTHIKNFPIALVG-APLAPAEM 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KrT95D	NP_524473.2	Pacs-1	676..1167	CDD:463027	288/491 (59%)
KrT95D	XP_061496549.1	None